INT59708

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Context Info
Confidence 0.44
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (YY1) chromosome organization (YY1) RNA binding (YY1)
plasma membrane (YY1) nucleus (YY1) intracellular (YY1)
Anatomy Link Frequency
SK-N-SH 2
YY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Morphine 7 99.74 Very High Very High Very High
Enkephalin 3 98.40 Very High Very High Very High
antagonist 1 92.88 High High
opioid receptor 3 91.12 High High
mu opioid receptor 1 88.76 High High
Delta opioid receptors 4 75.00 Quite High
agonist 2 63.04 Quite High
MU agonist 1 56.80 Quite High
Immobilon 1 53.76 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuroblastoma 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pretreatment of SK-N-SH cells with beta-funaltrexamine prevented down-regulation of delta receptors in response to chronic exposure to morphine but did not affect down-regulation of delta receptors in response to D-Pen2,D-Pen5-enkephalin.
Regulation (affect) of Negative_regulation (down-regulation) of delta in SK-N-SH associated with enkephalin and morphine
1) Confidence 0.44 Published 1993 Journal Mol. Pharmacol. Section Abstract Doc Link 8394999 Disease Relevance 0.07 Pain Relevance 1.21

General Comments

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