INT59786

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Context Info
Confidence 0.32
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.98
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (SERPINE2) cytosol (SERPINE2) extracellular space (SERPINE2)
extracellular region (SERPINE2)
Anatomy Link Frequency
embryo 1
pancreas 1
HPA 1
SERPINE2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 3 100.00 Very High Very High Very High
Pain 2 98.92 Very High Very High Very High
Neurotransmitter 1 94.20 High High
chemokine 4 93.16 High High
cytokine 1 92.56 High High
Inflammatory mediators 1 91.72 High High
Central nervous system 1 79.96 Quite High
Myofascial pain syndrome 1 75.00 Quite High
tetrodotoxin 1 67.04 Quite High
palliative 1 61.12 Quite High
Disease Link Frequency Relevance Heat
Nervous System Injury 4 100.00 Very High Very High Very High
Carcinoma 1 100.00 Very High Very High Very High
Reprotox - General 1 1 100.00 Very High Very High Very High
Apoptosis 1 100.00 Very High Very High Very High
Injury 3 99.96 Very High Very High Very High
Cancer 6 99.76 Very High Very High Very High
Recurrence 1 99.52 Very High Very High Very High
Pain 2 98.92 Very High Very High Very High
Disease 2 97.40 Very High Very High Very High
Stress 2 95.92 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Therefore, it is necessary for the dentist to be familiar with PNI and the HPA-axis in order to make an accurate diagnosis of TMD.
PNI Binding (familiar) of in HPA
1) Confidence 0.32 Published 1997 Journal Dent. Clin. North Am. Section Abstract Doc Link 9142484 Disease Relevance 0.45 Pain Relevance 0.12
PNI is frequently used by many human carcinomas, in particular by pancreas and prostate cancer, and is associated with tumor recurrence and pain in advanced patients.
PNI Binding (associated) of in pancreas associated with pain, cancer, carcinoma, recurrence and reprotox - general 1
2) Confidence 0.31 Published 2010 Journal Cytokine Growth Factor Rev. Section Abstract Doc Link 20060768 Disease Relevance 1.19 Pain Relevance 0.38
Based on these results we believe that although PNI is associated with considerable morbidity, and frequently a long stay in Intensive Care, there is evidence of spontaneous recovery of diaphragmatic function in 90% of the patients.
PNI Binding (associated) of associated with nervous system injury
3) Confidence 0.31 Published 1993 Journal Eur J Cardiothorac Surg Section Abstract Doc Link 8396949 Disease Relevance 0.40 Pain Relevance 0.06
PNI, in nanomolar concentrations, rescues spinal cord motor neurons from both naturally-occurring programmed cell death in the chick embryo as well as following injury in the neonatal mouse.
PNI Binding (following) of in embryo associated with injury, apoptosis and spinal cord
4) Confidence 0.30 Published 1996 Journal J. Neurobiol. Section Abstract Doc Link 8738754 Disease Relevance 0.95 Pain Relevance 0.22

General Comments

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