INT59952

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Context Info
Confidence 0.46
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gh, IGF1) extracellular space (Gh, IGF1) extracellular region (Gh, IGF1)
cytosol (Gh) mitochondrion (Gh) plasma membrane (Gh)
Gh (Mus musculus)
IGF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tolerance 1 77.80 Quite High
Clonidine 3 64.24 Quite High
Disease Link Frequency Relevance Heat
Osteogenesis Imperfecta 12 98.24 Very High Very High Very High
Disease 1 64.96 Quite High
Congenital Anomalies 1 42.80 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the somatomedin generation test, the OI children as a group showed a blunted response, with 13 of 22 having less than a 2-fold stimulation of somatomedin-C by GH.
GH Positive_regulation (stimulation) of somatomedin-C associated with osteogenesis imperfecta
1) Confidence 0.46 Published 1993 Journal J. Clin. Endocrinol. Metab. Section Abstract Doc Link 8421094 Disease Relevance 0.84 Pain Relevance 0.16

General Comments

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