INT59962

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Context Info
Confidence 0.49
First Reported 1993
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 3.00
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Pcsk4)
Anatomy Link Frequency
skin 1
spermatids 1
Pcsk4 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 2 25.00 Low Low
Inflammation 4 5.00 Very Low Very Low Very Low
topical agent 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycosis Fungoides 34 100.00 Very High Very High Very High
Apoptosis 60 98.88 Very High Very High Very High
Sezary Syndrome 28 97.92 Very High Very High Very High
Malignant Neoplastic Disease 34 96.36 Very High Very High Very High
Lymphatic System Cancer 22 91.20 High High
Squamous Cell Carcinoma 4 86.56 High High
T-cell Lymphoma 2 83.56 Quite High
Cancer 14 5.00 Very Low Very Low Very Low
Wrinkles 10 5.00 Very Low Very Low Very Low
Death 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furin transcript was detected in both germ and somatic cells, while PC4 transcript was found only in round spermatids.
Gene_expression (found) of PC4 in spermatids
1) Confidence 0.49 Published 1993 Journal FEBS Lett. Section Abstract Doc Link 8422932 Disease Relevance 0 Pain Relevance 0
Our data suggest that Pc 4-PDT preferentially induces apoptosis of CD4+CD7?
Spec (suggest) Gene_expression (suggest) of Pc 4 associated with apoptosis
2) Confidence 0.10 Published 2010 Journal Advances in Hematology Section Abstract Doc Link PMC3004392 Disease Relevance 1.49 Pain Relevance 0
In vivo Pc 4-PDT of MF skin also photodamages the antiapoptotic protein Bcl-2.


1.

Gene_expression (photodamages) of Pc 4 in skin associated with mycosis fungoides
3) Confidence 0.10 Published 2010 Journal Advances in Hematology Section Abstract Doc Link PMC3004392 Disease Relevance 1.50 Pain Relevance 0

General Comments

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