INT59970

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Context Info
Confidence 0.40
First Reported 1993
Last Reported 1995
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.11
Pain Relevance 0.71

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Edn1) extracellular region (Edn1) cell-cell signaling (Edn1)
cytoplasm (Edn1)
Anatomy Link Frequency
plasma 2
blood vessels 2
Edn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 13 96.32 Very High Very High Very High
qutenza 4 91.76 High High
anesthesia 1 87.32 High High
ischemia 2 80.40 Quite High
Disease Link Frequency Relevance Heat
Hypoxia 12 99.60 Very High Very High Very High
Natriuresis 1 97.48 Very High Very High Very High
Acute Renal Failure 3 81.52 Quite High
Cv Unclassified Under Development 2 80.40 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There was a time-dependent increase in plasma creatinine levels as well as in [125I]ET-1 binding to cortical membranes at 2, 5 and 24 hr postreperfusion.
Positive_regulation (increase) of ET-1 Binding (binding) of in plasma
1) Confidence 0.40 Published 1993 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8423536 Disease Relevance 0.31 Pain Relevance 0.17
Atrial natriuretic peptide (ANP) binding levels were decreased in smooth muscle of all blood vessels after 7 days of hypoxia, but endothelin-1 (ET-1) and vasoactive intestinal peptide (VIP) binding was unchanged.
Neg (unchanged) Positive_regulation (unchanged) of ET-1 Binding (binding) of in blood vessels associated with natriuresis and hypoxia
2) Confidence 0.35 Published 1995 Journal Eur. Respir. J. Section Abstract Doc Link 8666097 Disease Relevance 0.79 Pain Relevance 0.54

General Comments

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