INT60006

Context Info Confidence 0.40 First Reported 1993 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 1.07 Pain Relevance 0.59

nuclear envelope (Scgb1a1) extracellular space (Scgb1a1) extracellular region (Scgb1a1) endoplasmic reticulum (Scgb1a1) cytoplasm (Scgb1a1)

Anatomy Link Frequency blood 1 Scgb1a1 (Rattus norvegicus)

Pain Link Frequency Relevance Heat diclofenac 1 99.52 aspirin 1 91.44 cINOD 4 83.92 Paracetamol 1 80.48 cva 1 75.00 Inflammation 16 68.72 imagery 2 50.80 cytokine 2 24.00 anesthesia 4 5.00 Inflammatory response 4 5.00

Disease Link Frequency Relevance Heat Hemorrhage 6 100.00 Hyperoxia 2 97.00 Weight Gain 2 82.32 INFLAMMATION 18 78.40 Pneumonia 4 68.72 Pulmonary Disease 8 61.52 Asthma 2 61.16 Stress 10 37.20 Pressure And Volume Under Development 16 5.00 Body Weight 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A significant increase in the risk of UGB and use of diclofenac, phenylpropionic acid derivatives, and indomethacin was also found in the two exposure periods considered, while for piroxicam a significant association was only apparent in the analysis of 1-month exposure.

Positive_regulation (increase) of UGB associated with hemorrhage and diclofenac

1) Confidence 0.40 Published 1993 Journal Recenti Prog Med Section Abstract Doc Link 8430245 Disease Relevance 0.64 Pain Relevance 0.53

Enhanced lung permeability has been measured by increased Clara-cell protein in blood [21] or enhanced DTPA clearance in the lung [22] after ozone and hyperoxia.

Positive_regulation (increased) of Clara-cell protein in blood associated with hyperoxia

2) Confidence 0.04 Published 2005 Journal Part Fibre Toxicol Section Body Doc Link PMC1180470 Disease Relevance 0.43 Pain Relevance 0.03

Clara-cell protein was measured in perfusate using a sensitive latex immunoassay [21] with a detection limit 1 ?

Positive_regulation (measured) of Clara-cell protein

3) Confidence 0.03 Published 2005 Journal Part Fibre Toxicol Section Body Doc Link PMC1180470 Disease Relevance 0 Pain Relevance 0.03

General Comments

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