INT60043

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Context Info
Confidence 0.27
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Syn1) ligase activity (Syn1)
Syn1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 4 99.64 Very High Very High Very High
opiate 8 98.04 Very High Very High Very High
antagonist 1 97.76 Very High Very High Very High
Enkephalin 1 95.00 High High
Dynorphin 1 93.76 High High
Nerve growth factor 17 89.88 High High
dorsal root ganglion 2 77.12 Quite High
tolerance 1 76.88 Quite High
Spinal cord 2 76.12 Quite High
Analgesic 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Infection 3 95.20 Very High Very High Very High
Ganglion Cysts 2 77.12 Quite High
Apoptosis 6 5.00 Very Low Very Low Very Low
Increased Venous Pressure Under Development 4 5.00 Very Low Very Low Very Low
Neuroblastoma 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Fibrosarcoma 2 5.00 Very Low Very Low Very Low
Metastasis 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of the kappa-agonist U50488 on the up-regulation of synapsin I was dose dependent and was blocked by the kappa-opiate antagonist norbinaltor-phimine.
Regulation (regulation) of synapsin I associated with antagonist, agonist and opiate
1) Confidence 0.27 Published 1993 Journal J. Neurochem. Section Abstract Doc Link 8436965 Disease Relevance 0.15 Pain Relevance 1.24
For PC12 (DN-Akt) cells, cells were infected with lentivirus targeting Syn-1 (shSyn-1#2) or shControl at an MOI of 10.
Regulation (targeting) of Syn-1
2) Confidence 0.06 Published 2010 Journal J Biomed Sci Section Body Doc Link PMC2844376 Disease Relevance 0.17 Pain Relevance 0.09

General Comments

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