INT60073

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Context Info
Confidence 0.42
First Reported 1993
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.03
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Il2) extracellular region (Il2)
Anatomy Link Frequency
lungs 2
T cells 2
Il2 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 92.80 High High
Central nervous system 22 5.00 Very Low Very Low Very Low
Multiple sclerosis 12 5.00 Very Low Very Low Very Low
Inflammation 5 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Demyelination 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Skin Cancer 6 100.00 Very High Very High Very High
Cancer 4 100.00 Very High Very High Very High
Recurrence 2 98.04 Very High Very High Very High
Immunization 2 53.92 Quite High
Multiple Sclerosis 50 34.48 Quite Low
Central Nervous System Disease 21 5.00 Very Low Very Low Very Low
Autoimmune Disease 6 5.00 Very Low Very Low Very Low
INFLAMMATION 5 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Paralysis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Combining preimmunization with FECA and IL-2 and resection of local melanoma tumors decreased the mortality and the number of mice with local recurrence and metastatic melanoma tumors to the lungs.
Negative_regulation (decreased) of IL-2 Binding (preimmunization) of in lungs associated with cancer, skin cancer and recurrence
1) Confidence 0.42 Published 1993 Journal J Surg Oncol Section Abstract Doc Link 8441268 Disease Relevance 1.03 Pain Relevance 0.09
To investigate whether IL-2 recovers from the decrease of Treg differentiation caused by 1,25(OH)2D3, we added recombinant IL-2 (rIL-2) on the culture medium of CD4+ T cells in the presence of TGF-?
Negative_regulation (added) of IL-2 Binding (recombinant) of in T cells
2) Confidence 0.15 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2944871 Disease Relevance 0 Pain Relevance 0

General Comments

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