INT60115

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Context Info
Confidence 0.08
First Reported 1993
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 3.05
Pain Relevance 0.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F8) oxidoreductase activity (F8) extracellular region (F8)
cell adhesion (F8) plasma membrane (F8)
Anatomy Link Frequency
platelet 1
F8 (Homo sapiens)
Pain Link Frequency Relevance Heat
Angina 1 96.92 Very High Very High Very High
cytokine 1 89.92 High High
Percutaneous transluminal coronary angioplasty 2 87.60 High High
Inflammation 3 85.16 High High
spinal inflammation 1 84.60 Quite High
rheumatoid arthritis 1 83.64 Quite High
cva 70 82.40 Quite High
carpal tunnel syndrome 2 5.00 Very Low Very Low Very Low
peripheral neuropathy 2 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 5 100.00 Very High Very High Very High
Stable Angina Pectoris 1 96.92 Very High Very High Very High
Pathologic Constriction 4 95.56 Very High Very High Very High
Necrosis 1 90.96 High High
Cancer 3 90.60 High High
Familial Mediterranean Fever 1 88.08 High High
Osteomyelitis 1 86.88 High High
Mycobacterial Infection 1 86.28 High High
Inflammatory Bowel Disease 1 85.72 High High
Cardiovascular Disease 16 85.48 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It activates coagulation cascade through tissue factor stimulation and increased transcription of factor VIII, up regulates transcription of fibrinogen, increases von Willebrand's factor, and decreases protein S [29].
Transcription (transcription) of factor VIII
1) Confidence 0.08 Published 2005 Journal Int Semin Surg Oncol Section Body Doc Link PMC1232862 Disease Relevance 2.07 Pain Relevance 0.40
The following factors were thus assessed: lipid factors: cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol, apolipoprotein AI, apolipoprotein B; coagulation factors: fibrinogen, antithrombin III, fibrinopeptide A, factor VIII coagulant, factor VIII antigen, protein C; factors of physiological fibrinolysis: plasminogen, alpha 2-antiplasmin, tissue plasminogen activator and euglobulin clot lysis time before and after venous occlusion, plasminogen activator inhibitor before venous occlusion; and factors of platelet release: beta-thromboglobulin, platelet factor 4.
Transcription (assessed) of factor VIII coagulant in platelet associated with disorder of lipid metabolism
2) Confidence 0.00 Published 1993 Journal Int. J. Cardiol. Section Abstract Doc Link 8444504 Disease Relevance 0.99 Pain Relevance 0.18

General Comments

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