INT60181

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Context Info
Confidence 0.03
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (HTR5A) plasma membrane (HTR5A) cell cycle (Pik3c3)
cell division (Pik3c3) kinase activity (Pik3c3) signal transducer activity (HTR5A)
Anatomy Link Frequency
brain 1
HTR5A (Homo sapiens)
Pik3c3 (Mus musculus)
Pain Link Frequency Relevance Heat
Hippocampus 1 95.28 Very High Very High Very High
Sumatriptan 2 89.32 High High
Serotonin 3 75.00 Quite High
Disease Link Frequency Relevance Heat
Holoprosencephaly 1 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 5-HT5A gene colocalized with the mouse mutation reeler and the human mutation holoprosencephaly type 3, which both result in abnormal brain development, raising the possibility that the 5-HT5A receptor plays a role in brain development.
5-HT5A Binding (colocalized) of holoprosencephaly type 3 in brain associated with holoprosencephaly
1) Confidence 0.03 Published 1993 Journal Mol. Pharmacol. Section Abstract Doc Link 8450829 Disease Relevance 0.10 Pain Relevance 0.29

General Comments

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