INT60209

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Context Info
Confidence 0.69
First Reported 1993
Last Reported 2006
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 3.06
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (RYR1) transmembrane transport (RYR1) cytoplasm (RYR1)
Anatomy Link Frequency
heart 1
kidney 1
RYR1 (Homo sapiens)
Pain Link Frequency Relevance Heat
anesthesia 3 91.08 High High
Central nervous system 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 9 99.96 Very High Very High Very High
Malignant Hyperthermia 7 99.68 Very High Very High Very High
Disease 6 99.58 Very High Very High Very High
Heart Disease 1 99.16 Very High Very High Very High
Muscle Disease 3 97.96 Very High Very High Very High
Contracture 2 96.36 Very High Very High Very High
Body Weight 6 96.00 Very High Very High Very High
Myasthenia Gravis 1 94.88 High High
Frailty 2 93.96 High High
Hypertension 6 75.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Screening of the ryanodine receptor gene in 105 malignant hyperthermia families: novel mutations and concordance with the in vitro contracture test.
Transcription (Screening) of ryanodine receptor gene associated with contracture and malignant hyperthermia
1) Confidence 0.69 Published 1999 Journal Hum. Mol. Genet. Section Title Doc Link 10484775 Disease Relevance 1.16 Pain Relevance 0.09
Among the strains, MHS was found to be unique for the smallest kidney size and New Zealand strains for the greatest relative LV size when adjusted to allow for the influence of BP.
Transcription (found) of MHS in kidney associated with sprains and strains
2) Confidence 0.59 Published 1993 Journal Heart Vessels Section Abstract Doc Link 8454565 Disease Relevance 1.31 Pain Relevance 0.06
Reported studies on diseases associated with the dysfunction of the ryanodine receptor mainly concern with heart disease, although studies concerning its involvement with skeletal muscle in malignant hyperthermia, myasthenia gravis, and muscular dystrophy have been conducted.
Transcription (dysfunction) of ryanodine receptor in heart associated with heart disease, frailty, myasthenia gravis, malignant hyperthermia and disease
3) Confidence 0.07 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687630 Disease Relevance 0.58 Pain Relevance 0

General Comments

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