From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.37
First Reported 1993
Last Reported 2006
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.50
Pain Relevance 0.97

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ptgs1, Ptgs2) oxidoreductase activity (Ptgs1, Ptgs2) endoplasmic reticulum (Ptgs1, Ptgs2)
nucleus (Ptgs1, Ptgs2) cytoplasm (Ptgs1, Ptgs2) nuclear envelope (Ptgs1)
Ptgs1 (Mus musculus)
Ptgs2 (Mus musculus)
Pain Link Frequency Relevance Heat
aspirin 4 99.82 Very High Very High Very High
cINOD 6 95.84 Very High Very High Very High
COX2 6 94.00 High High
Inflammation 3 86.96 High High
Analgesic 1 76.16 Quite High
withdrawal 1 65.80 Quite High
cOX1 3 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 94.96 High High
Atherosclerotic Plaque 1 89.44 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Structural modeling and biochemical assays showed the ability of PGHS1 and PGHS2 to heterodimerize and form prostaglandins.
PGHS1 Binding (heterodimerize) of PGHS2
1) Confidence 0.37 Published 2006 Journal Nat. Med. Section Abstract Doc Link 16732282 Disease Relevance 0.33 Pain Relevance 0.38
Aspirin completely inhibited bis-oxygenation of arachidonate by PGH synthase-1; in contrast, aspirin-treated PGH synthase-2 metabolized arachidonate primarily to 15-hydroxyeicosatetraenoic acid (15-HETE) instead of PGH2.
PGH Binding (metabolized) of PGH2 associated with aspirin
2) Confidence 0.34 Published 1993 Journal J. Biol. Chem. Section Abstract Doc Link 8454631 Disease Relevance 0.17 Pain Relevance 0.58

General Comments

This test has worked.

Personal tools