INT60241

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Context Info
Confidence 0.06
First Reported 1993
Last Reported 1999
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.33
Pain Relevance 0.60

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (HMGCL) small molecule metabolic process (HMGCL) lyase activity (HMGCL)
mitochondrion organization (HMGCL) peroxisome (HMGCL) embryo development (HMGCL)
HMGCL (Homo sapiens)
Pain Link Frequency Relevance Heat
aspirin 3 89.04 High High
Paracetamol 2 82.72 Quite High
cINOD 7 75.00 Quite High
Pain 1 65.36 Quite High
Bile 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 75.00 Quite High
Exanthema 1 69.44 Quite High
Hepatocellular Cancer 1 66.04 Quite High
Pain 1 65.36 Quite High
Atherosclerosis 1 51.60 Quite High
Increased Venous Pressure Under Development 2 25.00 Low Low
Coronary Artery Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Pravastatin is a new lipid-lowering drug belonging to the class of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase inhibitors.
Negative_regulation (inhibitors) of 3-hydroxy-3-methylglutaryl
1) Confidence 0.06 Published 1993 Journal Clin Ther Section Abstract Doc Link 8458055 Disease Relevance 0.13 Pain Relevance 0.07
We also investigated the effect of indomethacin on LDL binding in the presence of the 3-hydroxy-3-methylglutaryl CoA (HMG CoA) reductase inhibitor, fluvastatin.
Negative_regulation (inhibitor) of 3-hydroxy-3-methylglutaryl
2) Confidence 0.02 Published 1999 Journal Eur. J. Pharmacol. Section Abstract Doc Link 10395027 Disease Relevance 0.19 Pain Relevance 0.54

General Comments

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