INT60340

Context Info Confidence 0.05 First Reported 1993 Last Reported 1993 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 2 Disease Relevance 0.64 Pain Relevance 0.59

plasma membrane (Grpr) signal transducer activity (Grpr)

Anatomy Link Frequency nerve 4 Grpr (Rattus norvegicus)

Pain Link Frequency Relevance Heat Enkephalin 4 100.00 Neuropeptide 6 97.08

Disease Link Frequency Relevance Heat Salivary Gland Disease 8 89.68 Cancer 2 76.56

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

A markedly enhanced expression of bombesin- and leu-enkephalin-(ENK)-like immunoreactivities (LI) in the ganglionic cells and a pronounced increase in the number of nerve fibers showing these immunoreactivities in the submandibular gland tissue following irradiation were observed 10 days after treatment.

Positive_regulation (enhanced) of Gene_expression (expression) of bombesin in nerve associated with enkephalin

1) Confidence 0.05 Published 1993 Journal Cell Tissue Res. Section Abstract Doc Link 8472309 Disease Relevance 0.32 Pain Relevance 0.29

A markedly enhanced expression of bombesin- and leu-enkephalin-(ENK)-like immunoreactivities (LI) in the ganglionic cells and a pronounced increase in the number of nerve fibers showing these immunoreactivities in the submandibular gland tissue following irradiation were observed 10 days after treatment.

Positive_regulation (increase) of Gene_expression (expression) of bombesin in nerve associated with enkephalin

2) Confidence 0.05 Published 1993 Journal Cell Tissue Res. Section Abstract Doc Link 8472309 Disease Relevance 0.32 Pain Relevance 0.30

General Comments

This test has worked.