INT60371

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Context Info
Confidence 0.41
First Reported 1993
Last Reported 1993
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 1
Disease Relevance 0.10
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) DNA binding (Fos) response to stress (Fos)
extracellular region (Pdyn) nucleolus (Fos) nucleus (Fos)
Anatomy Link Frequency
spinal cord neurons 1
Fos (Rattus norvegicus)
Pdyn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 3 99.84 Very High Very High Very High
agonist 3 99.82 Very High Very High Very High
Pain 2 99.20 Very High Very High Very High
Enkephalin 1 98.64 Very High Very High Very High
Serotonin 2 76.40 Quite High
intrathecal 1 75.88 Quite High
Raphe 1 63.96 Quite High
Disease Link Frequency Relevance Heat
Pain 1 99.20 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Molecular mechanisms of pain: serotonin1A receptor agonists trigger transactivation by c-fos of the prodynorphin gene in spinal cord neurons.
c-fos Positive_regulation (transactivation) of prodynorphin gene in spinal cord neurons associated with pain, agonist, enkephalin and spinal cord
1) Confidence 0.41 Published 1993 Journal Neuron Section Title Doc Link 8476611 Disease Relevance 0.10 Pain Relevance 0.70

General Comments

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