INT60646

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Context Info
Confidence 0.60
First Reported 1995
Last Reported 1997
Negated 2
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 1.76
Pain Relevance 3.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprd1) plasma membrane (Oprd1) cytoplasm (Oprd1)
signal transducer activity (Oprd1)
Anatomy Link Frequency
brain 4
NG108-15 2
embryonic kidney 2
Oprd1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 22 100.00 Very High Very High Very High
agonist 13 99.98 Very High Very High Very High
Opioid 9 99.98 Very High Very High Very High
Enkephalin 7 99.86 Very High Very High Very High
Immobilon 7 99.86 Very High Very High Very High
Analgesic 2 98.20 Very High Very High Very High
opiate 3 97.04 Very High Very High Very High
Pain 1 96.08 Very High Very High Very High
midbrain 2 94.24 High High
Kappa opioid receptor 2 93.28 High High
Disease Link Frequency Relevance Heat
Hypoxia 24 98.96 Very High Very High Very High
Pain 1 96.08 Very High Very High Very High
Injury 4 70.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Agonist regulation of the expression of the delta opioid receptor in NG108-15 cells.
Regulation (regulation) of Gene_expression (expression) of delta opioid receptor in NG108-15 associated with agonist and opioid receptor
1) Confidence 0.60 Published 1995 Journal FEBS Lett. Section Title Doc Link 8521954 Disease Relevance 0 Pain Relevance 0.64
Shorter term hypoxic treatments (one day and three days) did not induce changes in delta opioid receptor expression in whole brain homogenate.
Neg (not) Regulation (changes) of Gene_expression (expression) of delta opioid receptor in brain associated with hypoxia and opioid receptor
2) Confidence 0.27 Published 1996 Journal Neuroscience Section Abstract Doc Link 9157323 Disease Relevance 0.76 Pain Relevance 0.51
No consistent changes in delta opioid receptor expression were detected in these brain regions.
Neg (No) Regulation (changes) of Gene_expression (expression) of delta opioid receptor in brain associated with opioid receptor
3) Confidence 0.27 Published 1996 Journal Neuroscience Section Abstract Doc Link 9157323 Disease Relevance 0.90 Pain Relevance 0.59
Opioid regulation of the mouse delta-opioid receptor expressed in human embryonic kidney 293 cells.
Regulation (regulation) of Gene_expression (expressed) of delta-opioid receptor in embryonic kidney associated with opioid receptor and opioid
4) Confidence 0.04 Published 1997 Journal Mol. Pharmacol. Section Title Doc Link 9271350 Disease Relevance 0.10 Pain Relevance 1.71

General Comments

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