INT60699

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Context Info
Confidence 0.39
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Title
Documents 5
Total Number 5
Disease Relevance 1.94
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itgax)
Anatomy Link Frequency
macrophage 2
dendritic cells 2
lung 2
neutrophils 2
Itgax (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 7 99.98 Very High Very High Very High
narcan 2 99.82 Very High Very High Very High
opiate 2 96.76 Very High Very High Very High
peripheral neuropathy 1 75.00 Quite High
Pain 1 74.96 Quite High
Peripheral nervous system 1 66.96 Quite High
withdrawal 3 54.28 Quite High
cytokine 7 32.72 Quite Low
Inflammation 6 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mastocytoma 1 97.08 Very High Very High Very High
Neuropathy 7 95.76 Very High Very High Very High
Respiratory Syncytial Virus 62 93.32 High High
Infection 49 93.16 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 93.04 High High
Hypercalcemia 10 79.44 Quite High
Disease 5 78.48 Quite High
Dysesthesia 1 75.48 Quite High
Peripheral Neuropathy 1 75.00 Quite High
Nervous System Injury 1 48.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In two separate experiments, expression levels of CD11c normalized to GAPDH were nearly equal in CD11c+ (relative expression = 1.05 ± 0.06, n = 4) and CD8+ (relative expression = 1.08 ± 0.03) cells from the lung following RSV infection.
Negative_regulation (levels) of Gene_expression (expression) of CD11c in lung associated with infection and respiratory syncytial virus
1) Confidence 0.39 Published 2005 Journal Respir Res Section Body Doc Link PMC1184101 Disease Relevance 0.71 Pain Relevance 0
In contrast, in spleen, the numbers of B220+ B lymphocytes, CD11b+ monocytes, CD11c+ dendritic cells and Gr1+ granulocytes were similar in both K?
Negative_regulation (numbers) of Gene_expression (dendritic cells) of CD11c in dendritic cells
2) Confidence 0.20 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1899087 Disease Relevance 0.14 Pain Relevance 0.03
The expression of monocyte-macrophage markers and of major histocompatibility complex class II antigens appeared up-regulated in endoneurial ramified cells, while expression of CR3, a complement receptor involved in the process of phagocytosis, was down-regulated.
Negative_regulation (down-regulated) of Gene_expression (expression) of complement receptor in macrophage
3) Confidence 0.10 Published 1995 Journal Acta Neuropathol. Section Abstract Doc Link 8525797 Disease Relevance 1.09 Pain Relevance 0.15
Morphine suppresses complement receptor expression, phagocytosis, and respiratory burst in neutrophils by a nitric oxide and mu(3) opiate receptor-dependent mechanism.
Negative_regulation (suppresses) of Gene_expression (expression) of complement receptor in neutrophils associated with opiate and morphine
4) Confidence 0.01 Published 2000 Journal J. Neuroimmunol. Section Title Doc Link 11063831 Disease Relevance 0 Pain Relevance 0.68
[Morphine inhibits complement receptor expression, phagocytosis and oxidative burst by a nitric oxide dependent mechanism].
Negative_regulation (inhibits) of Gene_expression (expression) of complement receptor associated with morphine
5) Confidence 0.01 Published 2004 Journal Anasthesiol Intensivmed Notfallmed Schmerzther Section Title Doc Link 15098168 Disease Relevance 0 Pain Relevance 0.19

General Comments

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