INT60723

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.68
First Reported 1995
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 2.11
Pain Relevance 2.02

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Psen2) endoplasmic reticulum (Psen2) embryo development (Psen2)
protein complex (Psen2) cytosol (Psen2) peptidase activity (Psen2)
Psen2 (Mus musculus)
Pain Link Frequency Relevance Heat
Immobilon 6 99.02 Very High Very High Very High
Opioid 20 98.98 Very High Very High Very High
MU agonist 4 75.00 Quite High
Neuropeptide 2 73.80 Quite High
Chronic pancreatitis 3 73.28 Quite High
Inflammation 20 5.00 Very Low Very Low Very Low
Hippocampus 18 5.00 Very Low Very Low Very Low
long-term potentiation 8 5.00 Very Low Very Low Very Low
Thalamus 8 5.00 Very Low Very Low Very Low
Spinal cord 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 166 99.88 Very High Very High Very High
Pancreatic Cancer 2 98.76 Very High Very High Very High
Cancer 6 87.20 High High
Breast Cancer 3 86.56 High High
Adenocarcinoma 2 76.64 Quite High
Carcinoma 2 75.00 Quite High
Pancreatitis 3 73.28 Quite High
Malignant Neoplastic Disease 2 61.24 Quite High
Targeted Disruption 182 60.80 Quite High
Vascular Disease 16 58.84 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunolocalization of pS2, a putative growth factor, in pancreatic carcinoma.
Localization (Immunolocalization) of pS2 associated with pancreatic cancer
1) Confidence 0.68 Published 1995 Journal J. Gastroenterol. Hepatol. Section Title Doc Link 8527704 Disease Relevance 0.93 Pain Relevance 0.19
-secretase complexes containing either PS1 or PS2.
Localization (secretase) of PS2
2) Confidence 0.57 Published 2006 Journal Mol Neurodegener Section Body Doc Link PMC1513131 Disease Relevance 0.06 Pain Relevance 0
The mutations that have been found to be responsible for these cases of familial Alzheimer disease (FAD) are localized on the APP, PS1 or PS2 genes.
Localization (localized) of PS2 associated with alzheimer's dementia
3) Confidence 0.32 Published 2007 Journal Acta Neuropathol Section Body Doc Link PMC2100431 Disease Relevance 0.85 Pain Relevance 0
When cells were grown in the presence of FBS (in which case a minimal quantity of estrogens and/or opioids is provided by the serum), we observed either no effect of etorphine or ethylketocyclazocine (EKC) or an increase of secretion and/or production of pS2 and cathepsin D.
Localization (secretion) of pS2 associated with opioid and immobilon
4) Confidence 0.26 Published 1998 Journal J. Cell. Biochem. Section Abstract Doc Link 9831078 Disease Relevance 0.14 Pain Relevance 0.83
However, when cells were cultured in charcoal-stripped serum and in the absence of phenol red, the effect of the two opioids is different: EKC decreased the production and/or secretion of pS2 and cathepsin D, whereas etorphine increased their synthesis and/or secretion.
Localization (secretion) of pS2 associated with opioid and immobilon
5) Confidence 0.22 Published 1998 Journal J. Cell. Biochem. Section Abstract Doc Link 9831078 Disease Relevance 0.13 Pain Relevance 1.00

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox