INT60746

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Context Info
Confidence 0.16
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.23
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNF) extracellular space (TNF) extracellular region (TNF)
plasma membrane (TNF) intracellular (TNF) extracellular matrix organization (TNF)
Ltbr (Mus musculus)
TNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 1 81.64 Quite High
Pain 1 67.24 Quite High
Disease Link Frequency Relevance Heat
Weight Loss 2 97.16 Very High Very High Very High
Melanoma 4 96.56 Very High Very High Very High
Cancer 2 96.20 Very High Very High Very High
Toxicity 1 83.60 Quite High
Sarcoma 1 77.56 Quite High
Lymphatic System Cancer 1 76.56 Quite High
Leukemia 1 76.12 Quite High
Necrosis 1 70.68 Quite High
Pain 1 67.88 Quite High
Myalgia 1 67.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Neither the injection of an antimurine TNF alpha antibody nor an adenovirus, which produces a mutated TNF receptor inhibiting TNF alpha activity, into mice had any effect on either bryostatin-induced weight loss or melanoma tumor growth inhibition.
TNF receptor Negative_regulation (inhibiting) of TNF associated with weight loss, cancer and melanoma
1) Confidence 0.16 Published 1996 Journal Cancer Chemother. Pharmacol. Section Abstract Doc Link 8529289 Disease Relevance 1.23 Pain Relevance 0.11

General Comments

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