INT60793

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Context Info
Confidence 0.00
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.53

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TREH, Chrna9) small molecule metabolic process (TREH) hydrolase activity, acting on glycosyl bonds (TREH)
carbohydrate metabolic process (TREH)
Anatomy Link Frequency
muscle 2
TREH (Homo sapiens)
Chrna9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 1 95.80 Very High Very High Very High
agonist 4 94.84 High High
Central nervous system 1 93.00 High High
Potency 1 87.76 High High
antagonist 4 75.00 Quite High
local anesthetic 1 73.44 Quite High

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Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TMB-8 is much less potent (IC50 approximately 30-200 microM) as an inhibitor of high-affinity 3H-labeled acetylcholine or 125I-labeled alpha-bungarotoxin binding to human muscle nAChR, ganglionic alpha 3 beta 4-nAChR, or ganglionic alpha 7-nAChR subtypes.
Negative_regulation (inhibitor) of alpha-bungarotoxin Binding (binding) of nAChR in muscle
1) Confidence 0.00 Published 1995 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8531111 Disease Relevance 0 Pain Relevance 0.53

General Comments

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