INT60924

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Context Info
Confidence 0.44
First Reported 1995
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 1.04
Pain Relevance 3.89

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
brain 3
striatum 2
prefrontal 2
neuronal 1
spinal cord 1
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 47 100.00 Very High Very High Very High
Morphine 8 100.00 Very High Very High Very High
orphanin 4 100.00 Very High Very High Very High
Dopamine 4 100.00 Very High Very High Very High
substance P 6 99.92 Very High Very High Very High
MU agonist 1 99.92 Very High Very High Very High
depression 1 99.68 Very High Very High Very High
Opioid 4 99.28 Very High Very High Very High
withdrawal 9 97.40 Very High Very High Very High
isoflurane 5 95.84 Very High Very High Very High
Disease Link Frequency Relevance Heat
Stress 10 99.84 Very High Very High Very High
Depression 6 99.68 Very High Very High Very High
Syndrome 2 99.04 Very High Very High Very High
Urological Neuroanatomy 3 91.12 High High
Nociception 4 5.00 Very Low Very Low Very Low
Injury 4 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Ganglion Cysts 4 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Alterations in PD, c-fos, and SERT expression could contribute to the depression-like syndrome associated with psychostimulant withdrawal.
Regulation (contribute) of Regulation (Alterations) of c-fos associated with depression, syndrome and withdrawal
1) Confidence 0.44 Published 2009 Journal Synapse Section Abstract Doc Link 19116947 Disease Relevance 0.35 Pain Relevance 0.67
This experiment investigated the influence of age on prefrontal acetylcholine (ACh) release and Fos response in the hypothalamic paraventricular nucleus and the nucleus tractus solitarius (NTS) of rats following isoflurane anesthesia.
Spec (investigated) Regulation (influence) of Regulation (response) of Fos in prefrontal associated with anesthesia and isoflurane
2) Confidence 0.27 Published 2004 Journal Exp. Neurol. Section Abstract Doc Link 15530892 Disease Relevance 0 Pain Relevance 0.33
The ability of kappa opioid agonists to modulate dopamine-mediated behavior and Fos immunoreactivity was assessed in adult rats.
Regulation (modulate) of Regulation (immunoreactivity) of Fos associated with dopamine and mu agonist
3) Confidence 0.27 Published 1995 Journal Psychopharmacology (Berl.) Section Abstract Doc Link 8539319 Disease Relevance 0 Pain Relevance 0.61
The effect of [Phe(1)psi(CH(2)-NH)Gly(2)]-nociceptin(1-13)NH(2) on feeding and c-Fos immunoreactivity in selected brain sites.
Regulation (effect) of Regulation (immunoreactivity) of c-Fos in brain associated with orphanin
4) Confidence 0.26 Published 2000 Journal Brain Res. Section Title Doc Link 10973597 Disease Relevance 0 Pain Relevance 0.56
In search for the underlying neuronal mechanisms we investigated the influence of stress on morphine-induced c-fos expression in the brain, and, vice versa, the influence of morphine application on the brain's c-fos response to stress.
Regulation (influence) of in neuronal Regulation (response) of c-fos in brain associated with stress and morphine
5) Confidence 0.26 Published 2002 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 12225868 Disease Relevance 0.70 Pain Relevance 0.48
Topography of methylphenidate (ritalin)-induced gene regulation in the striatum: differential effects on c-fos, substance P and opioid peptides.
Regulation (effects) of Regulation (regulation) of c-fos in striatum associated with opioid and substance p
6) Confidence 0.26 Published 2005 Journal Neuropsychopharmacology Section Title Doc Link 15637641 Disease Relevance 0 Pain Relevance 0.41
It was reasoned that the magnitude of the c-fos response in the NTS and spinal cord depends both on the concentration of the chemicals and the duration of their presence in the stomach.
Regulation (depends) of in stomach Regulation (response) of c-fos in spinal cord associated with spinal cord
7) Confidence 0.26 Published 2005 Journal BMC Neurosci Section Body Doc Link PMC1239919 Disease Relevance 0 Pain Relevance 0.84

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