INT60990

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Context Info
Confidence 0.15
First Reported 1995
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 1.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Th) mitochondrion (Th) extracellular region (Bdnf)
nucleus (Th) cytoplasmic membrane-bounded vesicle (Bdnf) response to stress (Th)
Anatomy Link Frequency
Brain 1
Bdnf (Rattus norvegicus)
Th (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cocaine 6 99.52 Very High Very High Very High
Ventral tegmentum 7 99.40 Very High Very High Very High
Morphine 13 95.56 Very High Very High Very High
Nerve growth factor 3 82.36 Quite High
Dopamine 1 75.00 Quite High
Nucleus accumbens 3 28.96 Quite Low
addiction 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Drug Dependence 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Brain-derived neurotrophic factor, which by itself tended to decrease tyrosine hydroxylase levels in the ventral tegmental area, prevented the characteristic increase in tyrosine hydroxylase following morphine and cocaine exposure and reversed the increase in rats pretreated with morphine.
Brain-derived neurotrophic factor Negative_regulation (decrease) of tyrosine hydroxylase in Brain associated with ventral tegmentum, cocaine and morphine
1) Confidence 0.15 Published 1995 Journal Neuroscience Section Abstract Doc Link 8545003 Disease Relevance 0 Pain Relevance 1.17

General Comments

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