INT61028

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Context Info
Confidence 0.54
First Reported 1995
Last Reported 2001
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 6
Disease Relevance 0
Pain Relevance 3.58

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Jund) nucleus (Jund) DNA binding (Jund)
protein complex (Jund)
Anatomy Link Frequency
medial 5
lateral areas 3
neuronal 2
midline 2
Jund (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Thalamus 38 99.52 Very High Very High Very High
c fibre 20 97.04 Very High Very High Very High
Sciatic nerve 4 93.76 High High
Nucleus accumbens 3 91.92 High High
Enkephalin 1 84.80 Quite High
Morphine 4 79.84 Quite High
Vpl thalamus 4 75.88 Quite High
Pain 12 25.00 Low Low
nociceptor 4 25.00 Low Low
narcan 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Repression 4 46.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, in the medial thalamus it increased c-Jun and reduced the basal expression of JunD, whereas in the lateral thalamus it had no effect on c-Jun but again reduced the basal expression of JunD.
Negative_regulation (reduced) of Gene_expression (expression) of JunD in medial associated with thalamus
1) Confidence 0.54 Published 2001 Journal Neuroscience Section Abstract Doc Link 11744254 Disease Relevance 0 Pain Relevance 0.76
However, in the medial thalamus it increased c-Jun and reduced the basal expression of JunD, whereas in the lateral thalamus it had no effect on c-Jun but again reduced the basal expression of JunD.
Negative_regulation (reduced) of Gene_expression (expression) of JunD in medial associated with thalamus
2) Confidence 0.54 Published 2001 Journal Neuroscience Section Abstract Doc Link 11744254 Disease Relevance 0 Pain Relevance 0.74
A weak C-fiber input caused by noxious mechanical stimulation of the skin of one hindpaw did not induce expression of c-Fos, FosB, Krox-20 or Krox-24; but it did reduce the basal expressions of c-Jun and JunD in both the medial and lateral areas.
Negative_regulation (reduce) of Gene_expression (expressions) of JunD in lateral areas associated with c fibre
3) Confidence 0.54 Published 2001 Journal Neuroscience Section Abstract Doc Link 11744254 Disease Relevance 0 Pain Relevance 0.74
Expression of JunD was inhibited in intralaminar and midline thalamic nuclei.
Negative_regulation (inhibited) of Gene_expression (Expression) of JunD in midline
4) Confidence 0.51 Published 1995 Journal Brain Res. Section Abstract Doc Link 8548308 Disease Relevance 0 Pain Relevance 0.51
A weak C-fiber input caused by noxious mechanical stimulation of the skin of one hindpaw did not induce expression of c-Fos, FosB, Krox-20 or Krox-24; but it did reduce the basal expressions of c-Jun and JunD in both the medial and lateral areas.
Negative_regulation (reduce) of in medial Gene_expression (expressions) of JunD in lateral areas associated with c fibre
5) Confidence 0.18 Published 2001 Journal Neuroscience Section Abstract Doc Link 11744254 Disease Relevance 0 Pain Relevance 0.74
When neuronal cells are plated on top of the monolayers, the expression of Fra, c-Jun, JunD, and GFAP decreases in the astroglial cells.
Negative_regulation (decreases) of Gene_expression (expression) of JunD in neuronal
6) Confidence 0.08 Published 1996 Journal Brain Res. Mol. Brain Res. Section Abstract Doc Link 8738155 Disease Relevance 0 Pain Relevance 0.08

General Comments

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