INT61029

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Context Info
Confidence 0.49
First Reported 1995
Last Reported 2009
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0.82
Pain Relevance 2.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

aging (Fos) nucleolus (Fos) nucleus (Fos)
DNA binding (Fos) transcription factor binding (Fos) response to stress (Fos)
Anatomy Link Frequency
brain 2
caudate-putamen 2
Fos (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 11 99.98 Very High Very High Very High
Central grey 30 99.36 Very High Very High Very High
Morphine 13 99.24 Very High Very High Very High
Nucleus accumbens 3 98.84 Very High Very High Very High
tolerance 5 98.40 Very High Very High Very High
Thalamus 2 98.00 Very High Very High Very High
Analgesic 1 93.56 High High
Cannabinoid 23 90.48 High High
amygdala 4 85.52 High High
Antinociceptive 2 80.08 Quite High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 33 99.36 Very High Very High Very High
Anxiety Disorder 61 83.92 Quite High
Pain 5 68.24 Quite High
Panic Disorder 1 14.56 Low Low
Stress 2 5.00 Very Low Very Low Very Low
Agoraphobia 1 5.00 Very Low Very Low Very Low
Nociception 1 5.00 Very Low Very Low Very Low
Shock 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
JunB was induced in the same regions of the caudate-putamen as found for c-Fos, but was not induced in the nucleus accumbens or thalamus.
Positive_regulation (induced) of c-Fos Binding (found) of in caudate-putamen associated with nucleus accumbens and thalamus
1) Confidence 0.49 Published 1995 Journal Brain Res. Section Abstract Doc Link 8548308 Disease Relevance 0 Pain Relevance 0.49
Striatal c-Fos protein levels and AP-1 DNA binding activity were increased in rats receiving paired morphine compared with rats that did not receive morphine but not in rats receiving morphine without the CS.
Positive_regulation (increased) of c-Fos Binding (binding) of associated with morphine
2) Confidence 0.45 Published 1998 Journal Neuroreport Section Abstract Doc Link 9855286 Disease Relevance 0 Pain Relevance 1.13
CB1 agonists increases Fos expression [31] and brain metabolic activity in the
Positive_regulation (increases) of Fos Binding (activity) of in brain associated with agonist
3) Confidence 0.11 Published 2009 Journal Neural Plasticity Section Body Doc Link PMC2593468 Disease Relevance 0.82 Pain Relevance 0.77

General Comments

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