INT6105

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.69
First Reported 1984
Last Reported 2010
Negated 5
Speculated 8
Reported most in Abstract
Documents 133
Total Number 141
Disease Relevance 82.76
Pain Relevance 34.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL2) extracellular region (IL2) cell adhesion (IL2)
cell-cell signaling (IL2)
Anatomy Link Frequency
T-cell 11
lymphocytes 8
NK cell 6
plasma 4
blood 3
IL2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 883 100.00 Very High Very High Very High
Inflammation 595 100.00 Very High Very High Very High
antagonist 58 100.00 Very High Very High Very High
Inflammatory marker 7 100.00 Very High Very High Very High
Morphine 51 99.76 Very High Very High Very High
Fibrositis 9 99.76 Very High Very High Very High
Angina 18 99.56 Very High Very High Very High
dexamethasone 55 99.52 Very High Very High Very High
rheumatoid arthritis 305 99.44 Very High Very High Very High
Enkephalin 8 99.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cancer 1000 100.00 Very High Very High Very High
INFLAMMATION 673 100.00 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 383 100.00 Very High Very High Very High
Necrosis 75 100.00 Very High Very High Very High
Nociception 4 99.92 Very High Very High Very High
Malignant Neoplastic Disease 74 99.90 Very High Very High Very High
Bacterial Infection 21 99.76 Very High Very High Very High
Sleep Disorders 9 99.76 Very High Very High Very High
Lymphocytosis 3 99.74 Very High Very High Very High
Syndrome 549 99.68 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our present data suggest that the presence of intrauterine bacterial infection may stimulate the intrauterine production of IL-2, and that the stimulation of IL-2 and the reduction of progesterone caused by IL-2 may in part explain the mechanism of uterine contraction associated with intrauterine infection during pregnancy.
Positive_regulation (stimulation) of IL-2 in uterine associated with bacterial infection and infection
1) Confidence 0.69 Published 1994 Journal Eur. J. Endocrinol. Section Abstract Doc Link 8180676 Disease Relevance 0.39 Pain Relevance 0.07
Whereas in group T, IL-2 was unchanged 1 h after operation but was significantly elevated 3 and 24 h after operation.
Positive_regulation (elevated) of IL-2
2) Confidence 0.69 Published 2006 Journal J. Huazhong Univ. Sci. Technol. Med. Sci. Section Abstract Doc Link 17120754 Disease Relevance 0 Pain Relevance 1.29
Thus, an increase in the number of IL-2 secreting DCs in the PBMC preparations examined after the intervention, might explain the observed increase in IL-2 production in cultures derived from SMT-C and SMT-NC – treated subjects.
Spec (examined) Positive_regulation (increase) of IL-2
3) Confidence 0.69 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0.16 Pain Relevance 0
The observed IL-2 increase might also be due to an increase in the number of DCs.
Positive_regulation (increase) of IL-2
4) Confidence 0.69 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0.22 Pain Relevance 0
Significant increases in lymphocyte-activated killer cell cytotoxicity, antibody cellular cytotoxicity, and serum IL-2 receptor were also observed following both IL-2 and IL-2 plus IFN-alpha.
Positive_regulation (increases) of IL-2 in lymphocyte
5) Confidence 0.68 Published 1993 Journal Cancer Res. Section Abstract Doc Link 8443808 Disease Relevance 0.05 Pain Relevance 0
The serum levels of IL-6 and soluble IL-2 receptors were increased in our patients, however, the degree of the increase varied in each patient.
Positive_regulation (increased) of IL-2
6) Confidence 0.67 Published 2008 Journal BMC Pediatr Section Body Doc Link PMC2577649 Disease Relevance 1.55 Pain Relevance 0.14
The levels of cells and interleukin-2 were increased (P less than 0.001).
Positive_regulation (increased) of interleukin-2
7) Confidence 0.67 Published 1991 Journal Zhong Xi Yi Jie He Za Zhi Section Abstract Doc Link 1806305 Disease Relevance 0.84 Pain Relevance 0.10
The effects of Il-2 and IFNa could be upregulated by costimulation of effector cells with Il-1 or TNF alpha.
Positive_regulation (upregulated) of Il-2
8) Confidence 0.65 Published 1988 Journal Scand. J. Rheumatol. Suppl. Section Abstract Doc Link 3075075 Disease Relevance 0.77 Pain Relevance 0.29
In contrast, treatment with morphine resulted in a 31% and 36% increase in IFN gamma and IL-2 levels, respectively, during dual infection.
Positive_regulation (increase) of IL-2 associated with infection and morphine
9) Confidence 0.65 Published 2003 Journal J. Acquir. Immune Defic. Syndr. Section Abstract Doc Link 12640199 Disease Relevance 1.31 Pain Relevance 1.19
Inhibition of IL-2 activation by PB was demonstrated to result from a blockade of the mitogenic growth factor signal using the IL-2-dependent cell line HT-2.
Positive_regulation (activation) of IL-2
10) Confidence 0.65 Published 1986 Journal Transplantation Section Abstract Doc Link 3097893 Disease Relevance 0 Pain Relevance 0.21
IL-2 was increased in the AIS and SA groups compared to the control group (AIS 4.5 +/- 0.5 pg/ml; SA 6.3 +/- 0.6 pg/ml; controls 2.4 +/- 0.8 pg/ml, P < 0.05), whereas IL-6 was higher in the AIS group than in the other two groups (AIS 10.8 +/- 1.8 pg/ml; SA 1.8 +/- 0.8 pg/ml; controls 1.2 +/- 0.6 pg/ml, P < 0.0001).
Positive_regulation (increased) of IL-2 associated with angina and syndrome
11) Confidence 0.63 Published 1999 Journal Atherosclerosis Section Abstract Doc Link 10488965 Disease Relevance 1.77 Pain Relevance 0.66
They showed pronounced elevations of interleukin-2 (IL-2), IL-6, tumor necrosis factor-alpha, and interferon-gamma, 3-5 hours after the start of infusion.
Positive_regulation (elevations) of interleukin-2 associated with necrosis and cancer
12) Confidence 0.59 Published 2000 Journal J. Immunother. Section Abstract Doc Link 10687147 Disease Relevance 1.70 Pain Relevance 0.09
They showed pronounced elevations of interleukin-2 (IL-2), IL-6, tumor necrosis factor-alpha, and interferon-gamma, 3-5 hours after the start of infusion.
Positive_regulation (elevations) of IL-2 associated with necrosis and cancer
13) Confidence 0.59 Published 2000 Journal J. Immunother. Section Abstract Doc Link 10687147 Disease Relevance 1.71 Pain Relevance 0.09
Interleukin 2 levels in the affected cultures were found to increase with combined HTLV-I infection and morphine treatment.
Positive_regulation (increase) of Interleukin 2 associated with infection and morphine
14) Confidence 0.58 Published 1999 Journal DNA Cell Biol. Section Abstract Doc Link 10235111 Disease Relevance 1.58 Pain Relevance 0.53
Patients at the second dose level were treated according to the same schedule, in which the dose of IL-2 was increased to 3.6 x 10(6) IU/m2/day.
Positive_regulation (increased) of IL-2
15) Confidence 0.57 Published 1992 Journal J. Immunother. Section Abstract Doc Link 1322167 Disease Relevance 0.64 Pain Relevance 0.07
The concentration of interleukin 2 (IL-2) was measured in amniotic fluids that had been obtained by amniocentesis, transvaginal amniotomy or by transuterine amniocentesis performed at cesarean section in 50 pregnant women.
Positive_regulation (concentration) of IL-2 in amniotic fluids
16) Confidence 0.50 Published 1994 Journal Eur. J. Endocrinol. Section Abstract Doc Link 8180676 Disease Relevance 0.33 Pain Relevance 0.07
The concentration of interleukin 2 (IL-2) was measured in amniotic fluids that had been obtained by amniocentesis, transvaginal amniotomy or by transuterine amniocentesis performed at cesarean section in 50 pregnant women.
Positive_regulation (concentration) of interleukin 2 in amniotic fluids
17) Confidence 0.50 Published 1994 Journal Eur. J. Endocrinol. Section Abstract Doc Link 8180676 Disease Relevance 0.33 Pain Relevance 0.07
In the PCA patients, IL-2 was decreased in group M and increased in group F postoperatively.
Positive_regulation (increased) of IL-2
18) Confidence 0.50 Published 2006 Journal J. Huazhong Univ. Sci. Technol. Med. Sci. Section Abstract Doc Link 17120754 Disease Relevance 0 Pain Relevance 1.31
In the present study we have demonstrated that following a spinal manipulative intervention the in vitro synthesis of IL-2 increases significantly, both with and without cavitation, for at least the short term (20 min post-SMT).
Positive_regulation (increases) of IL-2 in spinal
19) Confidence 0.50 Published 2008 Journal Chiropr Osteopat Section Body Doc Link PMC2423359 Disease Relevance 0 Pain Relevance 0.04
The administration of interleukin 2 (IL-2) and lymphokine-activated killer (LAK) cells can mediate the regression of cancer.
Positive_regulation (mediate) of IL-2 associated with cancer
20) Confidence 0.50 Published 1989 Journal J. Clin. Oncol. Section Abstract Doc Link 2783338 Disease Relevance 0.38 Pain Relevance 0.04

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox