INT61076

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Context Info
Confidence 0.65
First Reported 1995
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 9
Total Number 9
Disease Relevance 3.52
Pain Relevance 1.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
T cell 2
epithelium 1
RHD (Homo sapiens)
Pain Link Frequency Relevance Heat
GABAergic 46 100.00 Very High Very High Very High
Neuritis 3 99.36 Very High Very High Very High
Peripheral nervous system 3 98.16 Very High Very High Very High
pregabalin 1 97.82 Very High Very High Very High
Inflammation 3 95.92 Very High Very High Very High
lacosamide 1 86.44 High High
vincristine 1 80.12 Quite High
gABA 59 79.20 Quite High
Glutamate 5 78.88 Quite High
Duloxetine 1 77.88 Quite High
Disease Link Frequency Relevance Heat
Rheumatic Fever 66 100.00 Very High Very High Very High
Rheumatic Heart Disease 9 100.00 Very High Very High Very High
Experimental Autoimmune Neuritis 3 99.36 Very High Very High Very High
Nicotine Addiction 68 97.08 Very High Very High Very High
Infection 30 96.92 Very High Very High Very High
Demyelinating Disease 3 96.84 Very High Very High Very High
INFLAMMATION 3 95.92 Very High Very High Very High
Syndrome 6 91.48 High High
Francisella Infection 1 83.96 Quite High
Asthma 4 82.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Considering the high growth of RF/RHD in Kyrgyzstan, it is necessary to note that accurate diagnosis of the GABHS infection is important.
Gene_expression (growth) of RHD associated with rheumatic fever, rheumatic heart disease and infection
1) Confidence 0.65 Published 2010 Journal The Open Rheumatology Journal Section Body Doc Link PMC3023070 Disease Relevance 1.11 Pain Relevance 0.06
Since human P2 is not readily available, we produced full-length recombinant human P2 protein (rhP2) in Escherichia coli.
Gene_expression (produced) of rhP2
2) Confidence 0.17 Published 1995 Journal J. Neuroimmunol. Section Abstract Doc Link 8550812 Disease Relevance 0.29 Pain Relevance 0.19
Studies of human T cell autoreactivity as well as efforts to use hP2 as a tolerogen will be facilitated by the large-scale expression of rhP2.
Gene_expression (expression) of rhP2 in T cell
3) Confidence 0.17 Published 1995 Journal J. Neuroimmunol. Section Abstract Doc Link 8550812 Disease Relevance 0.25 Pain Relevance 0.17
It has been also found in Rh. sanguineus and Rh. turanicus in Greece, Spain, Portugal, Switzerland, central Africa, and Mali (2,12,13).
Gene_expression (turanicus) of Rh
4) Confidence 0.13 Published 2008 Journal Emerging Infectious Diseases Section Body Doc Link PMC2600325 Disease Relevance 0.37 Pain Relevance 0
It has been also found in Rh. sanguineus and Rh. turanicus in Greece, Spain, Portugal, Switzerland, central Africa, and Mali (2,12,13).
Gene_expression (sanguineus) of Rh
5) Confidence 0.13 Published 2008 Journal Emerging Infectious Diseases Section Body Doc Link PMC2600325 Disease Relevance 0.37 Pain Relevance 0
It has been also found in Rh. sanguineus and Rh. turanicus in Greece, Spain, Portugal, Switzerland, central Africa, and Mali (2,12,13).
Gene_expression (turanicus) of Rh
6) Confidence 0.13 Published 2008 Journal Emerging Infectious Diseases Section Body Doc Link PMC2600325 Disease Relevance 0.37 Pain Relevance 0
Production of rhP2 allowed the generation of human T cell lines reactive to the autologous protein.
Gene_expression (Production) of rhP2 in T cell
7) Confidence 0.12 Published 1995 Journal J. Neuroimmunol. Section Abstract Doc Link 8550812 Disease Relevance 0.28 Pain Relevance 0.19
Abacavir sulfate/lamivudine, Adalimumab, AdCD40L, Adefovir, Adefovir dipivoxil, Ambrisentan, Amlodipine, Amlodipine besylate/olmesartan medoxomil, AN-2728, Apixaban, Aripiprazole, Armodafinil, Atazanavir sulfate, Atomoxetine hydrochloride, Atrasentan, Azacitidine, Bevacizumab, Blinatumomab, Bortezomib, Bosentan, Carfilzomib, Caspofungin acetate, Cediranib, Cetuximab, Choriogonadotropin alfa, Clevudine, Clindamycin phosphate/benzoyl peroxide, Clofarabine, Daidzeol, Darunavir, Dasatinib, Decitabine, Deferasirox, Deforolimus, Degarelix acetate, Denenicokin, Dexlansoprazole, Duloxetine hydrochloride, Elacytarabine, Enfuvirtide, Enoxaparin, Entecavir, Eribulin mesilate, Erlotinib hydrochloride, Escitalopram oxalate, Eslicarbazepine acetate, Eszopiclone, Etravirine, Ezetimibe/simvastatin, Forodesine hydrochloride, Fosamprenavir calcium, Gefitinib, Gemtuzumab ozogamicin, Golimumab, Imatinib mesylate, Imetelstat, Insulin gl'argine, Insulin glulisine, Interferon alfa-2b XL, Ivabradine hydrochloride, Lacosamide, Lenalidomide, Lintuzumab, Liposomal adriamycin, Liposomal belotecan, Liposome-encapsulated fentanyl, Lopinavir/ritonavir, Lutropin alfa, LY-207320, Maraviroc, Mecasermin, MKC-253, MP-470, NGR-TNF, Nilotinib hydrochloride monohydrate, Ofatumumab, Olmesartan medoxomil, Omacetaxine mepesuccinate, PAN-811, Panobinostat, Pegfilgrastim, Peginterferon alfa-2a, Peginterferon alfa-2b, Peginterferon alfa-2b/ribavirin, Pemetrexed disodium, Perospirone hydrochloride, PF-734200, Phentermine/topiramate, Pimecrolimus, Pitavastatin calcium, Plerixafor hydrochloride, Pregabalin, Raltegravir potassium, Ramelteon, Ranibizumab, Recombinant Bet V1, Recombinant human insulin, Regadenoson, rhITF, Romidepsin, Rosuvastatin calcium, Ruboxistaurin hydrochloride, Rufinamide, Sapropterin dihydrochloride Saracatinib, SB-73, SC-599, Seliciclib, Sirolimus-eluting stent, Sorafenib, Sunitinib malate, Tadalafil, Tanespimycin, Tapentadol hydrochloride, Tegaserod maleate, Telbivudine, Tenofovir disoproxil fumarate, Tenofovir disoproxil fumarate/emtricitabine, Tenofovir disoproxil fumarate/emtricitabine/efavirenz, Ticlopidine hydrochloride, Tigecycline, TST-10088, Tularemia vaccine, Valsartan/amlodipine besylate, Vandetanib, Vardenafil hydrochloride hydrate, Vincristine, Vorinostat, Yttrium 90 (90Y) ibritumomab tiuxetan.
Gene_expression (hydrochloride) of rhITF associated with vincristine, pregabalin, lacosamide, adalimumab, duloxetine and francisella infection
8) Confidence 0.01 Published 2009 Journal Methods Find Exp Clin Pharmacol Section Abstract Doc Link 20094643 Disease Relevance 0.08 Pain Relevance 0.25
RT-PCR was used to confirm gene expression of GABAergic system gene in large and small airway epithelium from heathy nonsmokers and healthy smokers.
Gene_expression (expression) of GABAergic system gene in epithelium associated with nicotine addiction and gabaergic
9) Confidence 0.01 Published 2010 Journal Respir Res Section Abstract Doc Link PMC2988726 Disease Relevance 0.40 Pain Relevance 0.53

General Comments

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