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Context Info
Confidence 0.09
First Reported 1996
Last Reported 2003
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 1.97
Pain Relevance 1.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pdgfc) extracellular region (Pdgfc) nucleus (Pdgfc)
cytoplasm (Pdgfc)
Anatomy Link Frequency
spinal cord 1
neural 1
Pdgfc (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 17 100.00 Very High Very High Very High
dorsal root ganglion 5 99.40 Very High Very High Very High
antagonist 3 99.36 Very High Very High Very High
nMDA receptor 4 99.02 Very High Very High Very High
intrathecal 6 97.86 Very High Very High Very High
Inflammation 1 94.40 High High
Inflammatory response 1 92.80 High High
Sciatic nerve 2 88.08 High High
Dorsal horn 4 77.68 Quite High
Analgesic 2 64.52 Quite High
Disease Link Frequency Relevance Heat
Ganglion Cysts 5 98.92 Very High Very High Very High
Hypersensitivity 6 98.84 Very High Very High Very High
Diabetic Nephropathy 6 97.76 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super

4 97.00 Very High Very High Very High
Inflammatory Bowel Disease 1 94.96 High High
Colitis 5 94.00 High High
INFLAMMATION 1 92.40 High High
Urological Neuroanatomy 3 71.20 Quite High
Neuropathic Pain 6 70.40 Quite High
Nociception 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To characterize further the neural involvement in local immune reactions, we evaluated the effect of intrathecal NMDA-receptor blocker dizocilpine maleate (MK-801) on the peripheral immune response itself and on spinal cord c-fos expression induced by the delayed-type hypersensitivity (DTH) response.
Gene_expression (expression) of cord in neural associated with hypersensitivity, spinal cord and intrathecal
1) Confidence 0.09 Published 1996 Journal J. Neurosci. Section Abstract Doc Link 8551356 Disease Relevance 0.47 Pain Relevance 0.34
Spinal cord NMDA receptors modulate peripheral immune responses and spinal cord c-fos expression after immune challenge in rats subjected to unilateral mononeuropathy.
Gene_expression (expression) of cord in spinal cord associated with nmda receptor, diabetic nephropathy and spinal cord
2) Confidence 0.09 Published 1996 Journal J. Neurosci. Section Title Doc Link 8551356 Disease Relevance 0.54 Pain Relevance 0.43
Accordingly, we investigated the effect of a selective neurokinin (NK) 2 receptor antagonist, nepadutant, on proto-oncogene expression in the L(6)-S(1) spinal cord as well as in dorsal root ganglion (DRG) neurons after either non-noxious colorectal distension (CRD) or trinitrobenzenesulfonic acid (TNBS)-induced colitis in the adult rat.
Gene_expression (expression) of cord in DRG associated with colitis, ganglion cysts, dorsal root ganglion, antagonist and spinal cord
3) Confidence 0.02 Published 2003 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 12490601 Disease Relevance 0.76 Pain Relevance 0.44

General Comments

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