INT61115

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Context Info
Confidence 0.66
First Reported 1995
Last Reported 2011
Negated 0
Speculated 1
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.99
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ppard) lipid binding (Ppard) cell proliferation (Ppard)
nucleus (Ppard) DNA binding (Ppard) lipid metabolic process (Ppard)
Anatomy Link Frequency
brain 1
Ppard (Mus musculus)
Pain Link Frequency Relevance Heat
Thalamus 1 93.04 High High
Inflammation 11 88.76 High High
Pain 2 85.28 High High
aspirin 10 51.72 Quite High
cINOD 28 50.00 Quite Low
agonist 9 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
COX2 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Intestinal Polyps 7 98.68 Very High Very High Very High
Colon Cancer 16 98.00 Very High Very High Very High
Diabetes Mellitus 23 94.72 High High
INFLAMMATION 12 88.76 High High
Adenoma 7 87.20 High High
Pain 2 85.28 High High
Stress 1 84.16 Quite High
Metastasis 1 80.16 Quite High
Recurrence 1 79.24 Quite High
Cancer 55 78.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Min mice that were Ppard-null
Localization (were) of Ppard-null
1) Confidence 0.66 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408682 Disease Relevance 1.51 Pain Relevance 0.07
-oxidation genes is further potentiated by the nuclear hormone receptor coactivator PGC-1, a target of cyclic AMP (cAMP) response element binding (CREB), whose levels are increased during fasting and in diabetes [37, 38].
Localization (potentiated) of nuclear hormone receptor associated with diabetes mellitus
2) Confidence 0.46 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952334 Disease Relevance 0.31 Pain Relevance 0
To determine the specific brain localization of rPPAR delta we performed in situ hybridization analysis.
Spec (determine) Localization (localization) of rPPAR delta in brain
3) Confidence 0.05 Published 1995 Journal Biochem. Biophys. Res. Commun. Section Abstract Doc Link 8554552 Disease Relevance 0.17 Pain Relevance 0.21

General Comments

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