INT61117

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Context Info
Confidence 0.68
First Reported 1995
Last Reported 2010
Negated 5
Speculated 7
Reported most in Body
Documents 158
Total Number 166
Disease Relevance 69.30
Pain Relevance 15.98

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Ppara) nucleus (Ppara) DNA binding (Ppara)
Anatomy Link Frequency
chondrocytes 3
ovary 3
heart 2
liver 2
neuronal 2
Ppara (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 2119 100.00 Very High Very High Very High
antagonist 248 100.00 Very High Very High Very High
Inflammation 966 99.98 Very High Very High Very High
cva 24 99.70 Very High Very High Very High
Potency 514 98.40 Very High Very High Very High
metalloproteinase 478 95.20 Very High Very High Very High
fibrosis 137 93.16 High High
Arthritis 224 92.80 High High
ischemia 42 92.72 High High
imagery 53 92.16 High High
Disease Link Frequency Relevance Heat
Targeted Disruption 204 100.00 Very High Very High Very High
INFLAMMATION 1195 99.98 Very High Very High Very High
Obesity 961 99.96 Very High Very High Very High
Renal Disease 35 99.92 Very High Very High Very High
Hepatocellular Cancer 262 99.76 Very High Very High Very High
Cv General 3 Under Development 35 99.70 Very High Very High Very High
Placental Insufficiency 30 99.52 Very High Very High Very High
Apoptosis 894 99.50 Very High Very High Very High
Atherosclerosis 61 99.50 Very High Very High Very High
Stress 125 99.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Recently, detailed studies of PPAR expression profiles in different tissues pointed to the roles these receptors play in inflammation control and cell proliferation.
Gene_expression (expression) of PPAR associated with inflammation
1) Confidence 0.68 Published 1999 Journal Cell. Mol. Life Sci. Section Abstract Doc Link 10412372 Disease Relevance 0.34 Pain Relevance 0.27
expression levels of PPAR?
Gene_expression (expression) of PPAR
2) Confidence 0.68 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0 Pain Relevance 0.05
Detailed study addressing expression of PPAR?
Gene_expression (expression) of PPAR
3) Confidence 0.68 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.17 Pain Relevance 0
expression of PPAR?
Gene_expression (expression) of PPAR
4) Confidence 0.68 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.08 Pain Relevance 0
expression of PPAR?
Gene_expression (expression) of PPAR
5) Confidence 0.68 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.32 Pain Relevance 0
In this regard, over-expression of PPAR-?
Gene_expression (expression) of PPAR
6) Confidence 0.67 Published 2009 Journal PPAR Research Section Body Doc Link PMC2696219 Disease Relevance 0.43 Pain Relevance 0.16
Some of the synthetic agonists of PPAR?
Gene_expression (agonists) of PPAR associated with agonist
7) Confidence 0.63 Published 2010 Journal PPAR Research Section Body Doc Link PMC2938460 Disease Relevance 1.43 Pain Relevance 0.12
upregulation by PPAR?
Gene_expression (by) of PPAR
8) Confidence 0.63 Published 2010 Journal PPAR Research Section Body Doc Link PMC2938460 Disease Relevance 1.06 Pain Relevance 0.34
Detection of PPAR?
Gene_expression (Detection) of PPAR
9) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.05 Pain Relevance 0
The antibody detects PPAR?
Gene_expression (detects) of PPAR
10) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0 Pain Relevance 0
level, as in mice with heterozygous (PPAR?
Gene_expression (as) of PPAR
11) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.19 Pain Relevance 0
First, in vitro studies demonstrated that PPAR?
Gene_expression (demonstrated) of PPAR
12) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.11 Pain Relevance 0
were used as positive controls for PPAR?
Gene_expression (controls) of PPAR
13) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0 Pain Relevance 0.03
The PPAR family
Gene_expression (family) of PPAR
14) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.36 Pain Relevance 0
raised against a C-terminus sequence of human and mouse PPAR?
Gene_expression (sequence) of PPAR
15) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0 Pain Relevance 0
functionality of PPAR?
Gene_expression (functionality) of PPAR
16) Confidence 0.59 Published 2008 Journal PPAR Research Section Body Doc Link PMC2519140 Disease Relevance 0.32 Pain Relevance 0.12
This suggested that the presence of PPAR-?
Gene_expression (presence) of PPAR
17) Confidence 0.58 Published 2009 Journal PPAR Research Section Body Doc Link PMC2696219 Disease Relevance 0.81 Pain Relevance 0.24
Thus, it is possible that PPAR-?
Spec (possible) Gene_expression (possible) of PPAR
18) Confidence 0.58 Published 2009 Journal PPAR Research Section Body Doc Link PMC2696219 Disease Relevance 1.30 Pain Relevance 0.35
agonist with no PPAR-?
Gene_expression (with) of PPAR associated with agonist
19) Confidence 0.58 Published 2009 Journal PPAR Research Section Abstract Doc Link PMC2696219 Disease Relevance 0.44 Pain Relevance 0.17
So far, these effects of PPAR-?
Gene_expression (effects) of PPAR
20) Confidence 0.58 Published 2009 Journal PPAR Research Section Body Doc Link PMC2696219 Disease Relevance 1.41 Pain Relevance 0.30

General Comments

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