INT61163

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Context Info
Confidence 0.16
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.57
Pain Relevance 1.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Pcyt1a) cytosol (Pcyt1a) biosynthetic process (Pcyt1a)
nucleotidyltransferase activity (Pcyt1a) cytoplasm (Pcyt1a)
Pcyt1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Morphine 8 99.30 Very High Very High Very High
Antinociceptive 8 96.16 Very High Very High Very High
antagonist 6 85.64 High High
Opioid 2 85.16 High High
Central grey 2 75.00 Quite High
antinociception 2 73.52 Quite High
Pain 2 26.56 Quite Low
nociceptor 4 25.00 Low Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 10 98.32 Very High Very High Very High
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Two of these mechanisms are unique to beta-endorphin, possess a high affinity for CTP and can be discriminated based on their differential sensitivity to naltrexone.
CTP Binding (affinity) of
1) Confidence 0.16 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8558458 Disease Relevance 0.24 Pain Relevance 0.60
The results of radioligand binding studies were consistent with these observations. [125I]-beta-Endorphin labeled a population of sites in the PAG which (compared to those labeled by [3H]morphine) displayed a significantly higher affinity for CTP.
CTP Binding (affinity) of associated with urological neuroanatomy and morphine
2) Confidence 0.16 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8558458 Disease Relevance 0.33 Pain Relevance 0.72

General Comments

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