INT61266

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Context Info
Confidence 0.23
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nfkb1, Itgam) cytosol (Nfkb1) signal transduction (Nfkb1)
mitochondrion (Nfkb1) cell adhesion (Itgam) DNA binding (Nfkb1)
Nfkb1 (Mus musculus)
Itgam (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 4 92.00 High High
cINOD 2 73.60 Quite High
Inflammatory response 1 59.04 Quite High
chemokine 1 50.24 Quite High
cytokine 1 49.84 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 6 92.00 High High
Necrosis 1 80.68 Quite High
Cancer 1 80.32 Quite High
Adhesions 3 56.00 Quite High
Injury 1 44.84 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since it has been documented that the expression of E-selectin and Mac-1 is regulated either directly or indirectly by the transcription factor NF kappa B, our studies provide in vivo evidence that tepoxalin is a potent inhibitor of NF kappa B-mediated events in animal models and this novel molecular mechanism clearly defines it as a new class of anti-inflammatory compounds.
NF kappa B Regulation (regulated) of Gene_expression (expression) of Mac-1 associated with inflammation
1) Confidence 0.23 Published 1996 Journal Eur. J. Immunol. Section Abstract Doc Link 8566054 Disease Relevance 0.65 Pain Relevance 0.32

General Comments

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