INT6129

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.70
First Reported 1980
Last Reported 2011
Negated 0
Speculated 4
Reported most in Abstract
Documents 63
Total Number 67
Disease Relevance 30.44
Pain Relevance 16.64

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP) cell-cell signaling (AVP) response to stress (AVP)
signal transducer activity (AVP) cytosol (AVP) extracellular space (AVP)
Anatomy Link Frequency
hypothalamus 8
pituitary 8
outflow 4
cleft 4
urine 4
AVP (Homo sapiens)
Pain Link Frequency Relevance Heat
Neuropeptide 172 100.00 Very High Very High Very High
Catecholamine 60 100.00 Very High Very High Very High
Nicotine 38 100.00 Very High Very High Very High
narcan 65 99.98 Very High Very High Very High
agonist 40 99.98 Very High Very High Very High
fluoxetine 12 99.98 Very High Very High Very High
Kappa opioid receptor 6 99.98 Very High Very High Very High
Dismenorea 12 99.84 Very High Very High Very High
Pain 42 99.74 Very High Very High Very High
opiate 18 99.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
Hyponatremia 363 100.00 Very High Very High Very High
Syndrome 87 100.00 Very High Very High Very High
Pressure And Volume Under Development 67 100.00 Very High Very High Very High
Cirrhosis 56 100.00 Very High Very High Very High
Adrenal Insufficiency 10 100.00 Very High Very High Very High
Hypoglycemia 16 99.98 Very High Very High Very High
Myocardial Infarction 113 99.96 Very High Very High Very High
Volume Depletion And Dehydration 14 99.96 Very High Very High Very High
Nicotine Addiction 20 99.84 Very High Very High Very High
Acute Renal Failure 13 99.84 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Naloxone decreases the inhibitory effect of ethanol on the release of arginine-vasopressin induced by physical exercise in man.
Positive_regulation (induced) of Localization (release) of arginine-vasopressin associated with narcan
1) Confidence 0.70 Published 2009 Journal J Neural Transm Section Title Doc Link 19649691 Disease Relevance 0 Pain Relevance 0.42
In order to establish whether ethanol exerts its inhibiting effect on the nicotine-induced release of arginine-vasopressin (AVP) by interacting with an opioid pathway, six normal volunteers were treated with naloxone (2 or 4 mg as IV bolus, plus 5 or 10 mg infused over 105 minutes) during (2 nonfilter) cigarette smoking and ethanol (50 mL to 110 mL of whiskey) drinking.
Spec (whether) Positive_regulation (induced) of Localization (release) of arginine-vasopressin associated with nicotine addiction, nicotine, narcan and opioid
2) Confidence 0.70 Published 1987 Journal Metab. Clin. Exp. Section Abstract Doc Link 3600293 Disease Relevance 0.24 Pain Relevance 0.42
Effect of naloxone on the inhibitory effect of melatonin on the release of arginine-vasopressin induced by physical exercise in man.
Positive_regulation (induced) of Localization (release) of arginine-vasopressin associated with narcan
3) Confidence 0.70 Published 2010 Journal Regul. Pept. Section Title Doc Link 20346989 Disease Relevance 0 Pain Relevance 0.40
Naloxone-sensitive endogenous opioids do not seem to be involved in the control of basal and hypoglycemia-induced AVP secretion.
Positive_regulation (induced) of Localization (secretion) of AVP associated with hypoglycemia, endogenous opioid and narcan
4) Confidence 0.69 Published 1990 Journal Neuroendocrinology Section Abstract Doc Link 2112727 Disease Relevance 0.56 Pain Relevance 0.66
Naloxone increases the nicotine-stimulated rise of vasopressin secretion in man.
Positive_regulation (increases) of Localization (secretion) of vasopressin associated with nicotine and narcan
5) Confidence 0.69 Published 1982 Journal Clin. Endocrinol. (Oxf) Section Title Doc Link 7094361 Disease Relevance 0 Pain Relevance 0.52
Nicotine stimulated vasopressin secretion in all subjects.
Positive_regulation (stimulated) of Localization (secretion) of vasopressin associated with nicotine
6) Confidence 0.69 Published 1982 Journal Clin. Endocrinol. (Oxf) Section Abstract Doc Link 7094361 Disease Relevance 0 Pain Relevance 0.46
Moreover, acute lowering of blood pressure facilitated the release of vasopressin and its osmoregulation while a chronic antihypertensive treatment did not interfere with a normal control of vasopressin secretion.
Positive_regulation (facilitated) of Localization (release) of vasopressin in blood
7) Confidence 0.69 Published 2003 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 14514019 Disease Relevance 0.32 Pain Relevance 0.06
It is concluded that the pathophysiology of premenstrual pain could imply increased vasopressin secretion.
Positive_regulation (increased) of Localization (secretion) of vasopressin associated with pain
8) Confidence 0.69 Published 1984 Journal Acta Obstet Gynecol Scand Section Abstract Doc Link 6542295 Disease Relevance 0.98 Pain Relevance 1.07
Opiates appear to be involved in mechanisms which suppress the osmotically mediated release of vasopressin, while opiate involvement in baroceptor-mediated release may be quite different.
Positive_regulation (mediated) of Localization (release) of vasopressin associated with opiate
9) Confidence 0.68 Published 1980 Journal Lancet Section Abstract Doc Link 6107725 Disease Relevance 0.09 Pain Relevance 0.48
About the transient increase in ADH secretion, we considered that hypothalamic disturbance in NMS might induce leakage of stored ADH from neuroendocrine neurons in it.
Positive_regulation (increase) of Localization (secretion) of ADH in neurons associated with neuroleptic malignant syndrome
10) Confidence 0.67 Published 1995 Journal Rinsho Shinkeigaku Section Abstract Doc Link 7781236 Disease Relevance 0.88 Pain Relevance 0.20
We believe that stress was caused more by greater surgical trauma than by the depth of anesthesia and anesthetic agents in Groups 2 and 3, when compared to Group 1; this is a possible mechanism of the increased AVP secretion.
Spec (possible) Positive_regulation (increased) of Localization (secretion) of AVP associated with stress, anesthesia and injury
11) Confidence 0.67 Published 1983 Journal Int J Clin Pharmacol Ther Toxicol Section Abstract Doc Link 6350197 Disease Relevance 0.19 Pain Relevance 0.10
Naloxone increases the angiotensin II stimulated rise of arginine vasopressin and oxytocin secretion in man.
Positive_regulation (increases) of Localization (secretion) of arginine vasopressin associated with narcan
12) Confidence 0.67 Published 1991 Journal Neuroendocrinology Section Title Doc Link 2041583 Disease Relevance 0 Pain Relevance 0.50
Endogenous agents including acetylcholine, angiotensin II, histamine, bradykinin, and neuropeptide Y have all been implicated in the stimulation of AVP release (Sladek 1983; Baylis 1989).
Positive_regulation (stimulation) of Localization (release) of AVP associated with neuropeptide and bradykinin
13) Confidence 0.64 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.42 Pain Relevance 0.51
Stress has been thought to induce the release of arginine vasopressin (AVP).
Positive_regulation (induce) of Localization (release) of vasopressin associated with stress
14) Confidence 0.61 Published 1986 Journal Psychoneuroendocrinology Section Abstract Doc Link 3786636 Disease Relevance 0.17 Pain Relevance 0.07
Hyponatraemia and the syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by psychotropic drugs.
Positive_regulation (induced) of Localization (secretion) of antidiuretic hormone associated with hyponatremia and syndrome
15) Confidence 0.60 Published 1995 Journal Drug Saf Section Title Doc Link 7619332 Disease Relevance 1.54 Pain Relevance 0.11
It responds by providing the stimulus to cortico-releasing hormone (CRH) neurons in the paraventricular nucleus of the hypothalamus to increase the secretion of principal neuropeptide CRH and arginine vasopressin (AVP) into the hypophyseal portal bloodstream.
Positive_regulation (increase) of Localization (secretion) of AVP in hypothalamus associated with neuropeptide
16) Confidence 0.58 Published 2006 Journal Chiropr Osteopat Section Body Doc Link PMC1629015 Disease Relevance 0.12 Pain Relevance 0.20
An example of the latter phenomenon is primary dysmenorrhoea, women with this condition having an increased secretion of vasopressin.
Positive_regulation (increased) of Localization (secretion) of vasopressin associated with dismenorea
17) Confidence 0.58 Published 1994 Journal Ann. N. Y. Acad. Sci. Section Abstract Doc Link 7978951 Disease Relevance 0.70 Pain Relevance 0.46
In order to establish whether ethanol exerts its inhibiting effect on the nicotine-induced release of arginine-vasopressin (AVP) by interacting with an opioid pathway, six normal volunteers were treated with naloxone (2 or 4 mg as IV bolus, plus 5 or 10 mg infused over 105 minutes) during (2 nonfilter) cigarette smoking and ethanol (50 mL to 110 mL of whiskey) drinking.
Spec (whether) Positive_regulation (nicotine-induced) of Localization (release) of AVP associated with nicotine addiction, nicotine, narcan and opioid
18) Confidence 0.50 Published 1987 Journal Metab. Clin. Exp. Section Abstract Doc Link 3600293 Disease Relevance 0.24 Pain Relevance 0.42
Stress has been thought to induce the release of arginine vasopressin (AVP).
Positive_regulation (induce) of Localization (release) of AVP associated with stress
19) Confidence 0.50 Published 1986 Journal Psychoneuroendocrinology Section Abstract Doc Link 3786636 Disease Relevance 0.17 Pain Relevance 0.07
Subsequently, vasopressin secretion that is paradoxically insufficient with respect to the level of hypovolaemia has been observed [3,10,12,14,19].
Positive_regulation (insufficient) of Localization (secretion) of vasopressin associated with pressure volume 2 under development
20) Confidence 0.50 Published 2005 Journal Crit Care Section Body Doc Link PMC1175907 Disease Relevance 0.61 Pain Relevance 0.09

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox