INT6133

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Context Info
Confidence 0.58
First Reported 1981
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 56
Total Number 57
Disease Relevance 42.80
Pain Relevance 8.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Serpinc1)
Anatomy Link Frequency
plasma 9
limb 2
heart 2
liver 1
radial 1
Serpinc1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cva 67 100.00 Very High Very High Very High
analgesia 4 99.56 Very High Very High Very High
Angina 25 98.68 Very High Very High Very High
abdominal pain 6 97.92 Very High Very High Very High
aspirin 15 97.28 Very High Very High Very High
Pain 23 96.72 Very High Very High Very High
anesthesia 6 96.72 Very High Very High Very High
intrathecal 1 96.32 Very High Very High Very High
methotrexate 8 93.92 High High
Arthritis 1 93.76 High High
Disease Link Frequency Relevance Heat
Deep Vein Thrombosis 25 99.92 Very High Very High Very High
Thrombosis Related Under Development 39 99.84 Very High Very High Very High
Increased Venous Pressure Under Development 16 99.84 Very High Very High Very High
Pulmonary Embolism 6 99.80 Very High Very High Very High
Thrombosis 71 99.70 Very High Very High Very High
Hematoma 113 99.68 Very High Very High Very High
Thrombophilia 12 99.58 Very High Very High Very High
Inborn Genetic Diseases 2 99.56 Very High Very High Very High
Syndrome 16 99.22 Very High Very High Very High
Congenital Anomalies 11 99.16 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The background and significance for the decrease in antithrombin III activity induced by n-3 and n-6 PUFA's in patients with ischaemic heart disease is unknown.
Negative_regulation (decrease) of antithrombin III in heart associated with coronary artery disease
1) Confidence 0.58 Published 1988 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 3060987 Disease Relevance 0.25 Pain Relevance 0.15
Results of coagulation tests were normal other than a slight decrease in antithrombin III.
Negative_regulation (decrease) of antithrombin III
2) Confidence 0.58 Published 1981 Journal South. Med. J. Section Abstract Doc Link 7244707 Disease Relevance 0.31 Pain Relevance 0.14
Antithrombin III (AT III) deficiency is a rare hereditary disease that predisposes a patient to thromboembolic complications.
Negative_regulation (deficiency) of Antithrombin III associated with inborn genetic diseases and cva
3) Confidence 0.58 Published 2001 Journal Rev Esp Anestesiol Reanim Section Abstract Doc Link 11446944 Disease Relevance 0.57 Pain Relevance 0.23
Mesenteric venous thrombosis in a patient with prothrombin 20210A mutation and antithrombin III deficiency: challenges to conventional anticoagulation--a case report.
Negative_regulation (deficiency) of antithrombin III associated with thrombosis related under development
4) Confidence 0.58 Published 2003 Journal Vasc Endovascular Surg Section Title Doc Link 12894373 Disease Relevance 0.47 Pain Relevance 0.18
Antithrombin III (AT III) deficiency is a rare inherited disorder which predisposes patients to thrombotic complications.
Negative_regulation (deficiency) of Antithrombin III
5) Confidence 0.58 Published 1993 Journal Can J Anaesth Section Abstract Doc Link 8403113 Disease Relevance 0.09 Pain Relevance 0.23
This patient had multiple risks for thrombosis including obesity, prolonged periods of bed rest, oral contraceptive use, and possibly hypercoagulability related to markedly decreased antithrombin III levels.
Negative_regulation (decreased) of antithrombin III associated with thrombophilia, obesity and thrombosis
6) Confidence 0.58 Published 1995 Journal J Adolesc Health Section Abstract Doc Link 8519788 Disease Relevance 1.16 Pain Relevance 0.09
Decreases in antithrombin III of this magnitude have not been previously reported in association with either oral contraceptives or extensive thromboses.
Negative_regulation (Decreases) of antithrombin III associated with thrombosis
7) Confidence 0.58 Published 1995 Journal J Adolesc Health Section Abstract Doc Link 8519788 Disease Relevance 0.82 Pain Relevance 0.11
[Anesthetic management for cesarean delivery in a pregnant patient with congenital antithrombin III deficiency and pulmonary thromboembolism].
Negative_regulation (deficiency) of antithrombin III associated with pulmonary embolism and cva
8) Confidence 0.42 Published 2001 Journal Rev Esp Anestesiol Reanim Section Title Doc Link 11446944 Disease Relevance 0.63 Pain Relevance 0.26
Antithrombin III deficiency, deep venous thrombosis, and oral contraceptive use.
Negative_regulation (deficiency) of Antithrombin III associated with cva and deep vein thrombosis
9) Confidence 0.42 Published 1995 Journal J Adolesc Health Section Title Doc Link 8519788 Disease Relevance 1.00 Pain Relevance 0.17
[Cesarean section in a patient with a congenital deficit of antithrombin III: apropos of a case].
Negative_regulation (deficit) of antithrombin III
10) Confidence 0.42 Published 1996 Journal Rev Esp Anestesiol Reanim Section Title Doc Link 8966355 Disease Relevance 0.27 Pain Relevance 0.12
The patient was initially felt to be at high risk for a congenital antithrombin III deficiency because of her profoundly low plasma level and thus treated with antithrombin III concentrates.
Negative_regulation (deficiency) of antithrombin III in plasma
11) Confidence 0.42 Published 1995 Journal J Adolesc Health Section Abstract Doc Link 8519788 Disease Relevance 1.12 Pain Relevance 0.11
Enoxaparin is a low-molecular-weight heparin (LMWH) derivative that exerts its anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa.
Negative_regulation (inhibitor) of antithrombin III
12) Confidence 0.42 Published 2007 Journal Expert Rev Cardiovasc Ther Section Abstract Doc Link 17489664 Disease Relevance 0.23 Pain Relevance 0.05
Cofactors for endogenous inhibitors of coagulation (antithrombin III and heparin cofactor II), heparin administration results in a hypocoagulable state.
Negative_regulation (inhibitors) of antithrombin III
13) Confidence 0.42 Published 1992 Journal J Clin Pharmacol Section Abstract Doc Link 1322434 Disease Relevance 0.30 Pain Relevance 0.05
Obstetrical analgesia in a parturient with antithrombin III deficiency.
Negative_regulation (deficiency) of antithrombin III associated with analgesia
14) Confidence 0.42 Published 1993 Journal Can J Anaesth Section Title Doc Link 8403113 Disease Relevance 0.09 Pain Relevance 0.27
[Mesenteric venous thrombosis and antithrombin III deficiency: diagnosis before an acute digestive hemorrhage].
Negative_regulation (deficiency) of antithrombin III associated with cva and deep vein thrombosis
15) Confidence 0.42 Published 1997 Journal J Mal Vasc Section Title Doc Link 9479609 Disease Relevance 0.74 Pain Relevance 0.14
A primary thrombotic disorder was suggested and antithrombin III deficiency was found.
Negative_regulation (deficiency) of antithrombin III
16) Confidence 0.42 Published 1988 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 3337617 Disease Relevance 0.90 Pain Relevance 0.17
Mesenteric venous thrombosis due to antithrombin III deficiency.
Negative_regulation (deficiency) of antithrombin III associated with thrombosis related under development
17) Confidence 0.42 Published 1988 Journal Arch. Pathol. Lab. Med. Section Title Doc Link 3337617 Disease Relevance 0.91 Pain Relevance 0.17
Recurrent lower extremity venous thrombosis consequent to antithrombin III deficiency causes a particularly fulminant postphlebitic syndrome with characteristic venographic findings.
Negative_regulation (deficiency) of antithrombin III in extremity associated with postphlebitic syndrome and thrombosis related under development
18) Confidence 0.38 Published 1990 Journal J. Vasc. Surg. Section Abstract Doc Link 2325220 Disease Relevance 0.82 Pain Relevance 0.12
A relatively uncommon, but potentially lethal, cause of the thrombosis is congenital antithrombin III deficiency.
Negative_regulation (deficiency) of antithrombin III associated with thrombosis
19) Confidence 0.38 Published 1990 Journal J. Vasc. Surg. Section Abstract Doc Link 2325220 Disease Relevance 0.44 Pain Relevance 0.03
Occult antithrombin III deficiency: a potentially lethal complication of the postphlebitic limb.
Negative_regulation (deficiency) of antithrombin III in limb associated with cva
20) Confidence 0.38 Published 1990 Journal J. Vasc. Surg. Section Title Doc Link 2325220 Disease Relevance 0.68 Pain Relevance 0.15

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