INT615

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Context Info
Confidence 0.62
First Reported 1976
Last Reported 2010
Negated 21
Speculated 8
Reported most in Abstract
Documents 66
Total Number 75
Disease Relevance 33.43
Pain Relevance 15.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Alb) extracellular space (Alb) extracellular region (Alb)
enzyme binding (Alb) DNA binding (Alb) protein complex (Alb)
Anatomy Link Frequency
liver 6
plasma 4
blood 3
cerebrospinal fluid 2
spinal 2
Alb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammatory marker 65 100.00 Very High Very High Very High
anesthesia 56 100.00 Very High Very High Very High
qutenza 15 100.00 Very High Very High Very High
narcan 6 100.00 Very High Very High Very High
intrathecal 4 100.00 Very High Very High Very High
Clonidine 4 100.00 Very High Very High Very High
Glutamate 8 99.84 Very High Very High Very High
Paracetamol 16 99.82 Very High Very High Very High
ischemia 50 99.74 Very High Very High Very High
tolerance 9 99.56 Very High Very High Very High
Disease Link Frequency Relevance Heat
Nicotine Addiction 247 100.00 Very High Very High Very High
INFLAMMATION 218 100.00 Very High Very High Very High
Diabetes Mellitus 72 100.00 Very High Very High Very High
Injury 52 100.00 Very High Very High Very High
Cirrhosis 46 100.00 Very High Very High Very High
Coronary Artery Disease 21 100.00 Very High Very High Very High
Increased Venous Pressure Under Development 20 100.00 Very High Very High Very High
Chronic Renal Failure 16 100.00 Very High Very High Very High
Myocardial Infarction 13 100.00 Very High Very High Very High
Proteinuria 7 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Serum albumin levels were unaffected by ibuprofen cream treatment.
Neg (unaffected) Regulation (unaffected) of Serum albumin
1) Confidence 0.62 Published 2003 Journal Drugs Exp Clin Res Section Abstract Doc Link 12951839 Disease Relevance 1.18 Pain Relevance 0.64
Control NAR rats transplanted with NAR hepatocytes (n = 8) showed no significant changes in plasma albumin levels.
Neg (no) Regulation (changes) of albumin in plasma
2) Confidence 0.60 Published 1993 Journal Transplantation Section Abstract Doc Link 8516804 Disease Relevance 0 Pain Relevance 0.20
The RBP concentration in plasma decreased significantly at 12 hr after the APAP administration, while the plasma albumin concentration was affected a little.
Neg (little) Regulation (affected) of albumin in plasma associated with paracetamol
3) Confidence 0.46 Published 2002 Journal Drug Metab. Pharmacokinet. Section Abstract Doc Link 15618709 Disease Relevance 0.16 Pain Relevance 0.36
The most marked changes in albumin and GFAP immunoreaction were seen after 2 weeks and persisted with mild intensities even after 10 weeks.
Regulation (changes) of albumin
4) Confidence 0.45 Published 2006 Journal Pain Section Abstract Doc Link 16806707 Disease Relevance 0.08 Pain Relevance 0.32
Defunctionalization of capsaicin-sensitive nerves 14-30 days before induction of inflammation prevented the "acute-phase" changes in protein contents in the albumin, alpha(1), alpha(2), and beta globulin fractions in response to induction of inflammation with zymosan.
Regulation (changes) of albumin in nerves associated with inflammation and qutenza
5) Confidence 0.45 Published 2006 Journal Neurosci. Behav. Physiol. Section Abstract Doc Link 16841154 Disease Relevance 0.28 Pain Relevance 0.55
The findings do not support a role for the enteric nervous system for the egg albumin induced changes in Cl- secretion.
Regulation (role) of albumin in egg
6) Confidence 0.45 Published 1989 Journal Agents Actions Section Abstract Doc Link 2512772 Disease Relevance 0.54 Pain Relevance 0.24
CONCLUSIONS: Acute systemic hypoxia does not affect the vascular permeability to albumin.
Neg (not) Regulation (affect) of albumin
7) Confidence 0.44 Published 1993 Journal Cardiovasc. Res. Section Body Doc Link 8221808 Disease Relevance 0 Pain Relevance 0
The influence of liver injury on the plasma concentrations of alpha 1-acid glycoprotein (AGP) and albumin was examined in several different models of chemically-induced liver injury.
Regulation (influence) of albumin in plasma associated with injury
8) Confidence 0.44 Published 1992 Journal Chem. Pharm. Bull. Section Abstract Doc Link 1446373 Disease Relevance 0.62 Pain Relevance 0.16
Interpenetrating network hydrogel beads of carboxymethylcellulose and egg albumin for controlled release of lipid lowering drug.
Regulation (Interpenetrating) of albumin in egg
9) Confidence 0.44 Published 2010 Journal J Microencapsul Section Title Doc Link 20163285 Disease Relevance 0 Pain Relevance 0.17
A discussion of the role of the liver in controlling inflammatory events, in relation to the synthesis of an anti-inflammatory protein has been given; the present work is an extension of this and describes the changes in concentration and synthesis rate of albumin, fibrinogen and alpha1 acid glycoprotein during adjuvant arthritis in the rat.
Regulation (changes) of albumin in liver associated with inflammation, experimental arthritis and arthritis
10) Confidence 0.42 Published 1976 Journal Agents Actions Section Abstract Doc Link 60050 Disease Relevance 1.09 Pain Relevance 0.40
There was an increase over the Alb control in animals injected with halothane, MAA-Alb, and MAA + halothane (P < 0.05).
Regulation (control) of Alb associated with halothane
11) Confidence 0.39 Published 2005 Journal BMC Anesthesiol Section Body Doc Link PMC1090549 Disease Relevance 0 Pain Relevance 0.50
The present study has controlled for several covariates including age, sex, ischemic heart disease, peripheral vascular disease, diabetes, albumin, residual renal function, and Kt/V.
Regulation (controlled) of albumin in heart associated with coronary artery disease, diabetes mellitus and increased venous pressure under development
12) Confidence 0.39 Published 2002 Journal BMC Nephrol Section Body Doc Link PMC103666 Disease Relevance 0.37 Pain Relevance 0
This study examined the effect of meclofenamate on proteinuria, serum albumin levels, serum cholesterol, serum triglycerides, renal function, BP, liver function tests, and hematologic values.
Spec (examined) Regulation (effect) of albumin in liver associated with proteinuria
13) Confidence 0.39 Published 1986 Journal Am. J. Kidney Dis. Section Abstract Doc Link 3788972 Disease Relevance 0.90 Pain Relevance 0.08
RESULTS: At the end of the study, 36% of the patients met the KDOQI recommendations for serum albumin levels (compared to only 6% prior to the project), and albumin levels overall improved.
Regulation (recommendations) of serum albumin
14) Confidence 0.34 Published 2008 Journal Nephrol News Issues Section Abstract Doc Link 18711879 Disease Relevance 0.50 Pain Relevance 0.08
When controlling for albumin, patients with diagnosis of dementia were more likely to show improvement in functional status than patients without a dementia diagnosis.
Regulation (controlling) of albumin
15) Confidence 0.33 Published 2003 Journal J Palliat Med Section Body Doc Link 12710571 Disease Relevance 0 Pain Relevance 0
We examined the effect of a 30% blood volume expansion with either blood, isotonic saline, or isotonic saline plus albumin on the release of immunoreactive-atrial natriuretic factor (IR-ANF) in conscious and barbiturate-anesthetized rats.
Spec (examined) Regulation (effect) of albumin in blood associated with natriuresis
16) Confidence 0.30 Published 1990 Journal J Pharmacol Methods Section Abstract Doc Link 2139484 Disease Relevance 0.10 Pain Relevance 0
Cholinesterase activities, total protein- and albumin concentrations in serum as well as in cerebrospinal fluid were significantly decreased after surgical intervention under spinal Bupivacaine anesthesia but remained unchanged following spinal Bupivacaine application without surgery.
Neg (unchanged) Regulation (unchanged) of albumin in spinal associated with anesthesia
17) Confidence 0.29 Published 2002 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 12512739 Disease Relevance 0 Pain Relevance 0.64
Effect of bupivacaine application on cholinesterase activities, total protein- and albumin concentration in serum and cerebrospinal fluid.
Regulation (Effect) of albumin in cerebrospinal fluid
18) Confidence 0.29 Published 2002 Journal Scand. J. Clin. Lab. Invest. Section Title Doc Link 12512739 Disease Relevance 0 Pain Relevance 0.51
There was no influence of intrathecal Bupivacaine application on the albumin ratio cerebrospinal fluid/serum, nor was there any significant alteration of total protein- or albumin concentrations and butyrylcholinesterase activity in the serum as a result of local injection of Bupivacaine to facet joints.
Neg (no) Regulation (influence) of albumin in facet associated with facet joint and intrathecal
19) Confidence 0.29 Published 2002 Journal Scand. J. Clin. Lab. Invest. Section Abstract Doc Link 12512739 Disease Relevance 0.06 Pain Relevance 0.61
One patient, who showed severe pruritus, without relevant elevation of serum bile acids before treatment, did not respond to albumin dialysis.
Neg (not) Regulation (respond) of albumin in bile associated with bile and pruritus
20) Confidence 0.29 Published 2004 Journal Liver Transpl. Section Abstract Doc Link 14755786 Disease Relevance 0.72 Pain Relevance 0.47

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