INT61519

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 1995
Last Reported 2011
Negated 1
Speculated 5
Reported most in Abstract
Documents 112
Total Number 118
Disease Relevance 89.29
Pain Relevance 18.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Mpo) extracellular space (Mpo) oxidoreductase activity (Mpo)
lysosome (Mpo)
Anatomy Link Frequency
neutrophil 21
kidney 10
lungs 8
liver 6
Plasma 4
Mpo (Mus musculus)
Pain Link Frequency Relevance Heat
metalloproteinase 31 99.48 Very High Very High Very High
Ultiva 16 99.14 Very High Very High Very High
methotrexate 9 98.88 Very High Very High Very High
Paracetamol 107 98.32 Very High Very High Very High
Calcitonin gene-related peptide 14 98.32 Very High Very High Very High
Morphine 408 98.22 Very High Very High Very High
Leflunomide 8 97.92 Very High Very High Very High
ischemia 163 97.72 Very High Very High Very High
Inflammation 2063 97.64 Very High Very High Very High
Inflammatory response 477 97.44 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 1057 100.00 Very High Very High Very High
Disease 696 100.00 Very High Very High Very High
Infection 719 99.96 Very High Very High Very High
Targeted Disruption 550 99.96 Very High Very High Very High
Myocardial Infarction 348 99.96 Very High Very High Very High
Burns 527 99.52 Very High Very High Very High
Sprains And Strains 537 99.40 Very High Very High Very High
Coronary Artery Disease 36 99.40 Very High Very High Very High
Injury 1675 99.28 Very High Very High Very High
Melioidosis 171 98.14 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Myeloperoxidase is primarily found in neutrophils, and levels of myeloperoxidase in tissues reflect neutrophil sequestration.
Gene_expression (found) of Myeloperoxidase in neutrophil
1) Confidence 0.78 Published 1995 Journal J Burn Care Rehabil Section Abstract Doc Link 8582922 Disease Relevance 0.69 Pain Relevance 0.05
There was a trend toward higher MPO levels in the kidney following renal I/R.
Gene_expression (levels) of MPO in kidney associated with urological neuroanatomy
2) Confidence 0.77 Published 2010 Journal APMIS Section Abstract Doc Link 20132173 Disease Relevance 1.34 Pain Relevance 0.32
After vascular perfusion, lungs were analyzed for their levels of EB dye and myeloperoxidase (MPO).
Spec (analyzed) Gene_expression (levels) of MPO in lungs associated with urological neuroanatomy
3) Confidence 0.77 Published 2009 Journal Toxicology Mechanisms and Methods Section Abstract Doc Link PMC2736052 Disease Relevance 1.90 Pain Relevance 0.12
This study is to explore the effect of remifentanil on inducible nitric oxide synthase (iNOS) expression, IL-6 and IL-10 levels, myeloperoxidase (MPO) activity, white blood cell count in bronchoalveolar (BALF), ALT and AST activity in septic mice.
Gene_expression (expression) of MPO in white blood cell associated with urological neuroanatomy and ultiva
4) Confidence 0.76 Published 2010 Journal Mol. Biol. Rep. Section Abstract Doc Link 19757155 Disease Relevance 0.17 Pain Relevance 0.34
Blood urea nitrogen, serum creatinine, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels in blood and glutathione (GSH) and malondialdehyde (MDA) levels, myeloperoxidase (MPO) activity and collagen contents in liver and kidney tissues were measured.
Gene_expression (levels) of myeloperoxidase in kidney associated with urological neuroanatomy
5) Confidence 0.74 Published 2005 Journal J Appl Toxicol Section Abstract Doc Link 15669031 Disease Relevance 0.30 Pain Relevance 0.74
Correspondingly, there was a trend toward a decrease in MPO levels in the lung, liver, kidney of PAF-treated endotoxemic mice.
Gene_expression (levels) of MPO in kidney associated with urological neuroanatomy
6) Confidence 0.69 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2714981 Disease Relevance 0.76 Pain Relevance 0.06
Myeloperoxidase levels were significantly higher only in the first phase (4 h; median and range; 537.5; 323.6-683.7 mU/ml; P < 0.01), whereas increased mean nitrate levels were detected in both phases (4 h: 19.0; 6.2-32 microM and 48 h: 13.7; 8.9-17.8 microM; P < 0.01).
Gene_expression (higher) of Myeloperoxidase
7) Confidence 0.67 Published 1999 Journal Peptides Section Abstract Doc Link 10503773 Disease Relevance 0.32 Pain Relevance 0.29
After vascular perfusion, lungs were analyzed for their levels of EB dye and myeloperoxidase (MPO).
Spec (analyzed) Gene_expression (levels) of myeloperoxidase in lungs associated with urological neuroanatomy
8) Confidence 0.67 Published 2009 Journal Toxicology Mechanisms and Methods Section Abstract Doc Link PMC2736052 Disease Relevance 1.89 Pain Relevance 0.12
To further quantify the degree of neutrophil infiltration into the peritoneal cavity, the MPO levels of both the peritoneal lavage cell pellets and supernatants were measured.
Gene_expression (levels) of MPO in peritoneal cavity associated with urological neuroanatomy
9) Confidence 0.67 Published 2004 Journal BMC Clin Pathol Section Body Doc Link PMC503395 Disease Relevance 0.40 Pain Relevance 0
It is interesting to note that P/I null mice demonstrated a higher MPO levels in their peritoneal lavage supernatants than the wild-type counterparts.
Gene_expression (levels) of MPO associated with urological neuroanatomy
10) Confidence 0.67 Published 2004 Journal BMC Clin Pathol Section Body Doc Link PMC503395 Disease Relevance 0.86 Pain Relevance 0
Subsequent secondary activation of its metabolites by myeloperoxidase (MPO) present in bone marrow results in the production of genotoxic quinines and reactive oxygen species.
Gene_expression (present) of myeloperoxidase in bone marrow associated with urological neuroanatomy
11) Confidence 0.66 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688356 Disease Relevance 0.74 Pain Relevance 0
Subsequent secondary activation of its metabolites by myeloperoxidase (MPO) present in bone marrow results in the production of genotoxic quinines and reactive oxygen species.
Gene_expression (present) of MPO in bone marrow associated with urological neuroanatomy
12) Confidence 0.66 Published 2008 Journal Biomarker Insights Section Body Doc Link PMC2688356 Disease Relevance 0.73 Pain Relevance 0
This study is to explore the effect of remifentanil on inducible nitric oxide synthase (iNOS) expression, IL-6 and IL-10 levels, myeloperoxidase (MPO) activity, white blood cell count in bronchoalveolar (BALF), ALT and AST activity in septic mice.
Gene_expression (levels) of myeloperoxidase in white blood cell associated with urological neuroanatomy and ultiva
13) Confidence 0.66 Published 2010 Journal Mol. Biol. Rep. Section Abstract Doc Link 19757155 Disease Relevance 0.17 Pain Relevance 0.33
CGRP(8-37) or combination of SR 140333 and SR 48968 diminished neutrophil accumulation, MPO levels and IL-1beta production, airway hyperresponsiveness was inhibited only by SR 48968.
Gene_expression (production) of MPO in neutrophil associated with urological neuroanatomy and calcitonin gene-related peptide
14) Confidence 0.66 Published 2007 Journal Regul. Pept. Section Abstract Doc Link 17291600 Disease Relevance 0.61 Pain Relevance 1.01
Myeloperoxidase (MPO) activity A was expressed as change of optical density (?
Gene_expression (expressed) of Myeloperoxidase associated with urological neuroanatomy
15) Confidence 0.66 Published 2010 Journal Crit Care Section Body Doc Link PMC2887192 Disease Relevance 0.10 Pain Relevance 0
Myeloperoxidase (MPO) activity A was expressed as change of optical density (?
Gene_expression (expressed) of MPO associated with urological neuroanatomy
16) Confidence 0.66 Published 2010 Journal Crit Care Section Body Doc Link PMC2887192 Disease Relevance 0.10 Pain Relevance 0
Blood urea nitrogen (BUN), serum creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST) levels in blood, and glutathione (GSH), malondialdehyde (MDA), oxidized protein levels and myeloperoxidase (MPO) activity in liver and kidney tissues were measured.
Gene_expression (levels) of MPO in kidney associated with urological neuroanatomy
17) Confidence 0.64 Published 2003 Journal J. Pineal Res. Section Abstract Doc Link 12823615 Disease Relevance 0.40 Pain Relevance 0.68
Blood urea nitrogen (BUN), serum creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST) levels in blood, and glutathione (GSH), malondialdehyde (MDA), oxidized protein levels and myeloperoxidase (MPO) activity in liver and kidney tissues were measured.
Gene_expression (levels) of MPO in kidney associated with urological neuroanatomy
18) Confidence 0.64 Published 2003 Journal J. Pineal Res. Section Abstract Doc Link 12823615 Disease Relevance 0.40 Pain Relevance 0.66
Myeloperoxidase (MPO) assay
Gene_expression (assay) of MPO associated with urological neuroanatomy
19) Confidence 0.64 Published 2008 Journal Mol Pain Section Body Doc Link PMC2279109 Disease Relevance 0.35 Pain Relevance 0.15
Myeloperoxidase (MPO) assay
Gene_expression (assay) of Myeloperoxidase associated with urological neuroanatomy
20) Confidence 0.64 Published 2008 Journal Mol Pain Section Body Doc Link PMC2279109 Disease Relevance 0.35 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox