INT61642

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Context Info
Confidence 0.31
First Reported 1995
Last Reported 2008
Negated 1
Speculated 1
Reported most in Abstract
Documents 5
Total Number 6
Disease Relevance 7.03
Pain Relevance 0.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (ACVRL1)
Anatomy Link Frequency
coronary artery 1
smooth muscle 1
ACVRL1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 7 96.04 Very High Very High Very High
Angina 2 94.08 High High
ischemia 3 93.72 High High
cva 3 89.92 High High
nud 1 88.40 High High
Pain 3 86.64 High High
imagery 10 81.16 Quite High
headache 1 59.12 Quite High
Central nervous system 3 43.76 Quite Low
Spinal cord 2 11.12 Low Low
Disease Link Frequency Relevance Heat
Telangiectasia 61 100.00 Very High Very High Very High
Fistula 5 100.00 Very High Very High Very High
Biliary Liver Cirrhosis 4 99.92 Very High Very High Very High
Malignant Neoplastic Disease 11 99.44 Very High Very High Very High
Brain Hemorrhage 39 99.00 Very High Very High Very High
Pressure And Volume Under Development 6 98.40 Very High Very High Very High
INFLAMMATION 5 96.04 Very High Very High Very High
Coronary Artery Disease 2 94.16 High High
Cv General 3 Under Development 5 94.08 High High
Stroke 5 93.32 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association of HHT with primary malignancy has rarely been reported.
HHT Binding (association) of associated with malignant neoplastic disease and telangiectasia
1) Confidence 0.31 Published 2002 Journal J. Formos. Med. Assoc. Section Abstract Doc Link 12517049 Disease Relevance 1.29 Pain Relevance 0.17
The genetic study was positive for ALK1, but it is not formally recognized as a pathogen by geneticists.
ALK1 Neg (not) Binding (recognized) of
2) Confidence 0.31 Published 2008 Journal Cardiovasc Intervent Radiol Section Body Doc Link PMC2705726 Disease Relevance 1.33 Pain Relevance 0.18
HHT has been shown to be associated with intrahepatic biliary stones and might have a causal role.
HHT Spec (might) Binding (associated) of associated with telangiectasia
3) Confidence 0.30 Published 1995 Journal Eur J Gastroenterol Hepatol Section Abstract Doc Link 8590149 Disease Relevance 1.74 Pain Relevance 0.07
Association of coronary artery-LV fistulas with HHT has not been reported and can pose a management dilemma in view of the risks of extensive cardiopulmonary surgery and potential complications of myocardial ischemia, stroke, and brain abscess.
HHT Binding (Association) of in coronary artery associated with coronary artery disease, telangiectasia, fistula, stroke, ischemia and brain abscess
4) Confidence 0.30 Published 2001 Journal Chest Section Abstract Doc Link 11591593 Disease Relevance 1.20 Pain Relevance 0.19
The spindle cells were strongly reactive for smooth muscle actin but negative for ALK-1.
ALK-1 Binding (negative) of in smooth muscle
5) Confidence 0.27 Published 2006 Journal Arch. Pathol. Lab. Med. Section Abstract Doc Link 17090200 Disease Relevance 1.01 Pain Relevance 0.28
Based on a series of 41 patients, Weinberg et al. conclude that immunostaining with CD30, EMA, ALK1, and granzyme has only minor additional value above H&E staining [73].
ALK1 Binding (immunostaining) of
6) Confidence 0.04 Published 2008 Journal J Hematop Section Body Doc Link PMC2713479 Disease Relevance 0.46 Pain Relevance 0

General Comments

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