INT61749

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Context Info
Confidence 0.42
First Reported 1996
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 9
Total Number 13
Disease Relevance 4.04
Pain Relevance 1.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
Heart 2
bile 1
Csi (Mus musculus)
Pain Link Frequency Relevance Heat
vincristine 30 98.78 Very High Very High Very High
Bile 5 97.42 Very High Very High Very High
visual analogue scale 6 96.00 Very High Very High Very High
Central nervous system 12 87.76 High High
anesthesia 20 82.24 Quite High
magnetoencephalography 2 68.92 Quite High
Versed 2 66.56 Quite High
Pain 12 66.16 Quite High
peripheral neuropathy 6 66.00 Quite High
Ultiva 2 66.00 Quite High
Disease Link Frequency Relevance Heat
Injury 107 100.00 Very High Very High Very High
Toxicity 30 99.46 Very High Very High Very High
Sleep Disorders 8 95.20 Very High Very High Very High
Medulloblastoma 150 92.80 High High
Bone Cancer 3 91.24 High High
Malignant Neoplastic Disease 9 90.76 High High
Recurrence 74 87.88 High High
Cancer 117 86.52 High High
Osteogenic Sarcomas 6 83.92 Quite High
Cognitive Disorder 3 83.92 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment protocols evaluating the addition of combined and adjuvant vincristine-based chemotherapy to CSI have led to the conclusion that a reduction in CSI doses from 35.2 to 23.4 Gy does not decrease survival rates.
Negative_regulation (reduction) of CSI associated with vincristine
1) Confidence 0.42 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2939548 Disease Relevance 0.39 Pain Relevance 0.08
In nine (group IV) of 12 patients with recurrent stones NT, C, CSI, PL, BA, TLC, TP, and bile acid spectrum remained nearly unchanged as compared to their pretreatment values, whereas in three (groups I-III) of 12 cases a decrease in C, CSI, and TP was observed during therapy.
Negative_regulation (decrease) of CSI in bile associated with bile
2) Confidence 0.37 Published 1996 Journal Dig. Dis. Sci. Section Abstract Doc Link 8601364 Disease Relevance 0.74 Pain Relevance 0.24
After returning EMG at o1:34 a.m, the second dose of atracurium was injected 15 mg intravenously at 1:36 leading to complete EMG recession and increasing BS to 20–30% and decreasing CSI to 20–40.
Negative_regulation (decreasing) of CSI
3) Confidence 0.37 Published 2008 Journal Cases J Section Body Doc Link PMC2561013 Disease Relevance 0.21 Pain Relevance 0.23
Concomitant with decreasing EMG, CSI was decreased from 100 to 70.
Negative_regulation (decreased) of CSI
4) Confidence 0.37 Published 2008 Journal Cases J Section Body Doc Link PMC2561013 Disease Relevance 0.45 Pain Relevance 0.16
RESULTS: The overall prevalence of CSI among all trauma patients was 3.7%.
Negative_regulation (prevalence) of CSI
5) Confidence 0.37 Published 2008 Journal Neurosurg Focus Section Body Doc Link 18980470 Disease Relevance 0 Pain Relevance 0
In our case, the patient had received a CSI dose of 35.2 Gy, a boost of 55 Gy in combination with concomitant and adjuvant chemotherapy.
Negative_regulation (received) of CSI
6) Confidence 0.30 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2939548 Disease Relevance 0.99 Pain Relevance 0.12
In our group of patients, both acute and chronic therapy-related toxicity was moderate, even though CSI doses were reduced to 23.4 Gy in only four patients (20%), all of whom were subjected to chemotherapy-containing regimens.
Negative_regulation (reduced) of CSI associated with toxicity
7) Confidence 0.30 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2939548 Disease Relevance 0.53 Pain Relevance 0.15
Activity in cSI and iSII was not affected. (3) Passive movement of the hand ipsilateral to the side of noxious stimulation resulted in significant attenuation of cSI.
Negative_regulation (attenuation) of cSI
8) Confidence 0.10 Published 2004 Journal Pain Section Abstract Doc Link 14715394 Disease Relevance 0 Pain Relevance 0.16
Inhibition in cSI was considered to be mainly due to an interaction in SI by the signals ascending from the stimulated and movement hand.
Negative_regulation (Inhibition) of cSI
9) Confidence 0.09 Published 2004 Journal Pain Section Abstract Doc Link 14715394 Disease Relevance 0 Pain Relevance 0.23
Heart rate (HR), mean arterial pressure (MAP) and CSI values were analyzed from baseline before the beginning of propofol infusion (T0) until loss of CR; CSI and PropCp, CSI and anaesthetic planes, and PropCp and anaesthetic planes were compared using correlation analysis.
Spec (analyzed) Negative_regulation (loss) of CSI in Heart
10) Confidence 0.08 Published 2009 Journal Res. Vet. Sci. Section Abstract Doc Link 19339028 Disease Relevance 0 Pain Relevance 0
Heart rate (HR), mean arterial pressure (MAP) and CSI values were analyzed from baseline before the beginning of propofol infusion (T0) until loss of CR; CSI and PropCp, CSI and anaesthetic planes, and PropCp and anaesthetic planes were compared using correlation analysis.
Spec (analyzed) Negative_regulation (loss) of CSI in Heart
11) Confidence 0.08 Published 2009 Journal Res. Vet. Sci. Section Abstract Doc Link 19339028 Disease Relevance 0 Pain Relevance 0
Number of missed CSI, such as number of clinically important CSI not identified during initial ED visit.
Negative_regulation (Number) of CSI associated with injury
12) Confidence 0.06 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.37 Pain Relevance 0
Number of missed CSI, such as number of clinically important CSI not identified during initial ED visit.
Negative_regulation (number) of CSI associated with injury
13) Confidence 0.06 Published 2007 Journal Implement Sci Section Body Doc Link PMC1802999 Disease Relevance 0.37 Pain Relevance 0

General Comments

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