INT61757

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Context Info
Confidence 0.48
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 3
Disease Relevance 2.29
Pain Relevance 0.62

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA binding (A1cf) mRNA processing (A1cf) endoplasmic reticulum (A1cf)
nucleus (A1cf) intracellular (A1cf) cytoplasm (A1cf)
Anatomy Link Frequency
colon 2
A1cf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
COX2 12 83.20 Quite High
Inflammation 3 73.88 Quite High
cINOD 3 62.12 Quite High
Disease Link Frequency Relevance Heat
Aberrant Crypt Foci 18 100.00 Very High Very High Very High
Body Weight 3 88.52 High High
INFLAMMATION 6 73.88 Quite High
Cancer 3 66.36 Quite High
Toxicity 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
At this time, nimesulide at doses of 50, 100 and 200 ppm had reduced the numbers of azoxymethane-induced ACF to 75%, 71% and 65% respectively compared to the control.
Negative_regulation (reduced) of Positive_regulation (induced) of ACF associated with aberrant crypt foci
1) Confidence 0.48 Published 1996 Journal J. Cancer Res. Clin. Oncol. Section Abstract Doc Link 8601574 Disease Relevance 0.77 Pain Relevance 0.21
The number of azoxymethane-induced ACF per colon in the group given 200 ppm nimesulide was almost the same as in those given 200 piroxicam, and lower than that in the group given 200 ppm sulindac.
Negative_regulation (number) of Positive_regulation (induced) of ACF in colon associated with aberrant crypt foci
2) Confidence 0.36 Published 1996 Journal J. Cancer Res. Clin. Oncol. Section Abstract Doc Link 8601574 Disease Relevance 0.75 Pain Relevance 0.21
At this time, nimesulide at doses of 50, 100 and 200 ppm had reduced the numbers of azoxymethane-induced ACF to 75%, 71% and 65% respectively compared to the control.
Negative_regulation (numbers) of Positive_regulation (induced) of ACF associated with aberrant crypt foci
3) Confidence 0.36 Published 1996 Journal J. Cancer Res. Clin. Oncol. Section Abstract Doc Link 8601574 Disease Relevance 0.77 Pain Relevance 0.21

General Comments

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