INT61784

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Context Info
Confidence 0.51
First Reported 1996
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 27
Total Number 27
Disease Relevance 11.46
Pain Relevance 2.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CENPJ) cytoskeleton (CENPJ) cell division (CENPJ)
cytoplasm (CENPJ)
Anatomy Link Frequency
lung 4
respiratory 3
plasma 2
nasal 1
upper 1
CENPJ (Homo sapiens)
Pain Link Frequency Relevance Heat
depression 84 96.72 Very High Very High Very High
anesthesia 61 95.76 Very High Very High Very High
Inflammation 21 84.88 Quite High
Inflammatory stimuli 1 79.92 Quite High
Regional anesthesia 9 79.68 Quite High
Analgesic 15 79.28 Quite High
Opioid 55 77.84 Quite High
cINOD 7 74.92 Quite High
transcutaneous nerve stimulation 3 67.76 Quite High
Angina 1 65.92 Quite High
Disease Link Frequency Relevance Heat
Obstructive Sleep Apnea 621 99.96 Very High Very High Very High
Sleep Disorders 243 99.32 Very High Very High Very High
Obesity 58 98.36 Very High Very High Very High
Obstructive Airway Disease 10 98.36 Very High Very High Very High
Airway Obstruction 64 98.12 Very High Very High Very High
Respiratory Failure 48 97.20 Very High Very High Very High
Emergencies 3 96.78 Very High Very High Very High
Recurrence 10 95.36 Very High Very High Very High
Apnoea 363 94.84 High High
Insulin Resistance 15 93.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Another limitation of the study was that nasal CPAP therapy was not titrated under polysomnographic monitoring but increased gradually to 10 cm/H2O or to the highest tolerated number.
Neg (not) Positive_regulation (increased) of CPAP in nasal
1) Confidence 0.51 Published 2008 Journal Heart Fail Rev Section Body Doc Link PMC2698052 Disease Relevance 0.47 Pain Relevance 0
Mean HAMD and SDS scores were significantly reduced (P < 0.01) after two weeks whereas the SASS was only significantly increased (P < 0.01) from four weeks (Figure 3).
Positive_regulation (increased) of SASS
2) Confidence 0.45 Published 2010 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2951748 Disease Relevance 0.13 Pain Relevance 0
This is supported by the observed reduction in anteroposterior diameter at the level of the soft palate during propofol anesthesia and the subsequent increase in this measurement during nasal CPAP application.


Positive_regulation (increase) of CPAP in soft palate
3) Confidence 0.41 Published 1996 Journal Anesthesiology Section Body Doc Link 8602656 Disease Relevance 0 Pain Relevance 0
Fourteen patients were studied, ten of whom were able to tolerate CPAP for at least three months.
Positive_regulation (tolerate) of CPAP
4) Confidence 0.37 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650593 Disease Relevance 1.01 Pain Relevance 0.08
Furthermore, increased upper airway resistance may persist despite increases in CPAP settings to abolish features of airflow limitation (Monsterrat 1995).
Positive_regulation (increases) of CPAP in upper
5) Confidence 0.36 Published 2006 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2671821 Disease Relevance 0.16 Pain Relevance 0
These trials were performed either at the emergency department or at the ICU and not in an environment such as a coronary care unit (CCU) which is often not suited to use mechanical ventilators that are normally necessary for CPAP.
Positive_regulation (necessary) of CPAP associated with emergencies
6) Confidence 0.35 Published 2007 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2233641 Disease Relevance 0.52 Pain Relevance 0
HAMD) and the increase in SASS score from baseline to endpoint (?
Positive_regulation (increase) of SASS
7) Confidence 0.32 Published 2010 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2951748 Disease Relevance 0.29 Pain Relevance 0.04
The independent variables influencing continued use of CPAP were CPAP usage at 3 months (with a relative risk [RR] of stopping CPAP of 13.8 comparing <2 hours vs ?
Positive_regulation (stopping) of CPAP
8) Confidence 0.26 Published 2006 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2671821 Disease Relevance 0.40 Pain Relevance 0
Eighty-four per cent of subjects continued to use CPAP 12 months after commencing the therapy and the use of CPAP plateaued only after 4 years, with 68% continuing to adhere to therapy (Figure 3).
Positive_regulation (use) of CPAP
9) Confidence 0.26 Published 2006 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2671821 Disease Relevance 0.25 Pain Relevance 0
Plasma cortisol was increased in group CPAP (P < 0.01) and in group T (P < 0.001) during weaning, and in group T after extubation (P < 0.01) (Table 3).
Positive_regulation (increased) of CPAP in Plasma
10) Confidence 0.20 Published 2004 Journal Crit Care Section Body Doc Link PMC420062 Disease Relevance 0 Pain Relevance 0
Cortisol increased significantly during weaning in the CPAP group but not in the PS group.
Positive_regulation (increased) of CPAP
11) Confidence 0.13 Published 2004 Journal Crit Care Section Body Doc Link PMC420062 Disease Relevance 0.55 Pain Relevance 0.06
Urinary VMA increased in group PS (P < 0.05) and in group T (P < 0.001) during weaning, and increased in group CPAP (P < 0.01) and in group T (P < 0.001) post extubation (Table 5).
Positive_regulation (increased) of CPAP
12) Confidence 0.13 Published 2004 Journal Crit Care Section Body Doc Link PMC420062 Disease Relevance 0.07 Pain Relevance 0.03
However, the increases in EELV after EPAP and CPAP were consistently greater before methacholine infusion (P < 0.005).


Positive_regulation (increases) of CPAP
13) Confidence 0.12 Published 2004 Journal Crit Care Section Body Doc Link PMC420031 Disease Relevance 0 Pain Relevance 0
Participants previously diagnosed with OSAS, underwent a similar standard polysomnography trial CPAP treatment (CPAP Respironics, RemStar Plus, Murrysville, Pennsylvania, USA) along with a mask pressure monitoring as a substitute in measurement of oronasal flow.
Positive_regulation (underwent) of CPAP associated with obstructive sleep apnea
14) Confidence 0.11 Published 2008 Journal J Negat Results Biomed Section Body Doc Link PMC2607253 Disease Relevance 1.41 Pain Relevance 0.17
Lung units with the longest time constants or highest auto-PEEP levels require higher levels of CPAP to produce reductions in the inflation work in these diseased areas, whereas lung regions with shorter time constants or less auto-PEEP become overinflated at higher CPAP levels.
Positive_regulation (levels) of CPAP in lung
15) Confidence 0.09 Published 2004 Journal Crit Care Section Body Doc Link PMC420031 Disease Relevance 0.39 Pain Relevance 0
Petrof and coworkers [6] applied increasing levels of CPAP (5, 10, and 15 cmH2O) to mechanically ventilated patients and showed a progressive reduction in work of breathing despite a simultaneous increase in EELV.
Positive_regulation (increasing) of CPAP
16) Confidence 0.08 Published 2004 Journal Crit Care Section Body Doc Link PMC420031 Disease Relevance 0.45 Pain Relevance 0
The more positive end-expiratory Ppl values had the lowest increase in EELV after EPAP and CPAP (r = 0.42, P < 0.05).
Positive_regulation (increase) of CPAP
17) Confidence 0.08 Published 2004 Journal Crit Care Section Body Doc Link PMC420031 Disease Relevance 0.30 Pain Relevance 0
We noted that, for similar levels of IPAP, EPAP, and CPAP, EELV increased to a much lesser degree during methacholine infusion.
Positive_regulation (increased) of CPAP
18) Confidence 0.08 Published 2004 Journal Crit Care Section Body Doc Link PMC420031 Disease Relevance 0.16 Pain Relevance 0
Recurrent hypoxaemia may be better treated with CPAP along with oxygen rather than oxygen alone.[1] It is recommended that patients who use CPAP preoperatively should use CPAP postoperatively, as it may reduce the risk of airway obstruction and respiratory depression.[4051] Actually, even in absence of sleep apnoea, CPAP improved oxygenation after abdominal surgery.[53] Continuous positive airway pressure, however, should be used only after patients are awake, alert, and feasible (e.g. when patients are not ambulating).
Positive_regulation (use) of CPAP in respiratory associated with apnoea, depression, respiratory failure and airway obstruction
19) Confidence 0.06 Published 2008 Journal Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine Section Body Doc Link PMC2738308 Disease Relevance 0.72 Pain Relevance 0.61
Recurrent hypoxaemia may be better treated with CPAP along with oxygen rather than oxygen alone.[1] It is recommended that patients who use CPAP preoperatively should use CPAP postoperatively, as it may reduce the risk of airway obstruction and respiratory depression.[4051] Actually, even in absence of sleep apnoea, CPAP improved oxygenation after abdominal surgery.[53] Continuous positive airway pressure, however, should be used only after patients are awake, alert, and feasible (e.g. when patients are not ambulating).
Positive_regulation (use) of CPAP in respiratory associated with apnoea, depression, respiratory failure and airway obstruction
20) Confidence 0.06 Published 2008 Journal Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine Section Body Doc Link PMC2738308 Disease Relevance 0.72 Pain Relevance 0.60

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