INT61823

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Context Info
Confidence 0.01
First Reported 1996
Last Reported 2000
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 3
Disease Relevance 1.64
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (TGFB3) aging (TGFB3) extracellular region (TGFB3)
plasma membrane (TGFB3) nucleus (TGFB3) embryo development (TGFB3)
Anatomy Link Frequency
plasma 1
TGFB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 2 98.98 Very High Very High Very High
Angina 2 78.16 Quite High
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hypercalcemia 8 85.20 High High
Angina 2 78.16 Quite High
Disease 4 75.12 Quite High
Multiple Myeloma 8 75.00 Quite High
Bone Cancer 3 75.00 Quite High
Coronary Artery Disease 2 75.00 Quite High
Atherosclerosis 4 69.44 Quite High
Paralysis 1 50.48 Quite High
Severe Combined Immunodeficiency 3 36.60 Quite Low
Osteolysis 1 26.68 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TGFbeta3 levels were similar in the three groups, but elevated CD105/TGFbeta3 levels were noted in patients with NCA compared with those with TVD and healthy individuals (P< or =0.02).
Positive_regulation (elevated) of TGFbeta3
1) Confidence 0.01 Published 2000 Journal Atherosclerosis Section Abstract Doc Link 10996361 Disease Relevance 0.42 Pain Relevance 0.08
TGFbeta3 levels were similar in the three groups, but elevated CD105/TGFbeta3 levels were noted in patients with NCA compared with those with TVD and healthy individuals (P< or =0.02).
Positive_regulation (elevated) of TGFbeta3
2) Confidence 0.01 Published 2000 Journal Atherosclerosis Section Abstract Doc Link 10996361 Disease Relevance 0.42 Pain Relevance 0.08
Bone-resorbing human and murine cytokines such as interleukin-6 (IL-6), IL-1 alpha or beta, TGF-alpha, lymphotoxin, and TNF alpha were not significantly increased in ARH-77 mouse sera or marrow plasma, compared with control mice, although ARH-77 cells produce IL-6 and lymphotoxin in vitro.
Neg (not) Positive_regulation (increased) of TGF-alpha in plasma associated with cytokine
3) Confidence 0.01 Published 1996 Journal Blood Section Abstract Doc Link 8608240 Disease Relevance 0.80 Pain Relevance 0.05

General Comments

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