INT61910

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Context Info
Confidence 0.01
First Reported 1996
Last Reported 2010
Negated 0
Speculated 1
Reported most in Abstract
Documents 6
Total Number 7
Disease Relevance 3.00
Pain Relevance 0.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Slc3a2) plasma membrane (Slc3a2) carbohydrate metabolic process (Slc3a2)
Anatomy Link Frequency
monocytes 1
platelet 1
lung 1
Slc3a2 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 236 95.80 Very High Very High Very High
positron emission tomography 111 95.24 Very High Very High Very High
Percutaneous transluminal coronary angioplasty 3 93.56 High High
Paracetamol 1 89.88 High High
Angina 2 25.00 Low Low
headache 2 14.56 Low Low
cytokine 1 11.40 Low Low
Somatostatin 24 5.00 Very Low Very Low Very Low
anesthesia 18 5.00 Very Low Very Low Very Low
ketamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 655 99.42 Very High Very High Very High
Adenocarcinoma 33 99.32 Very High Very High Very High
Colon Cancer 142 98.24 Very High Very High Very High
Small Cell Lung Cancer 20 98.24 Very High Very High Very High
Lung Cancer 49 96.60 Very High Very High Very High
Solid Tumor 2 94.68 High High
Nose Bleeds 1 93.84 High High
Ecchymosis 1 93.28 High High
Cardiovascular Disease 1 92.96 High High
Follicular Lymphoma 25 86.80 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of fluorescein-labelled monoclonal antibody 197 to peripheral monocytes showed a rapid and persistently decreased mean fluorescein intensity, indicated binding of administered 197 to the monocytes in vivo.
monoclonal Binding (Binding) of in monocytes
1) Confidence 0.01 Published 1996 Journal Br. J. Haematol. Section Abstract Doc Link 8616043 Disease Relevance 0.57 Pain Relevance 0.09
In contrast, anti-TAG (tumor associated glycoprotein)-72 monoclonal antibodies are highly specific for binding to a variety of adenocarcinomas, including colorectal cancer.
monoclonal Binding (binding) of associated with adenocarcinoma, cancer and colon cancer
2) Confidence 0.01 Published 2010 Journal World J Surg Oncol Section Abstract Doc Link PMC2924340 Disease Relevance 0.75 Pain Relevance 0.42
A murine monoclonal antibody that binds to and blocks the IIb/IIIa receptor inhibits the binding of fibrinogen to platelets and thus inhibits platelet aggregation.
monoclonal Binding (binds) of in platelet
3) Confidence 0.01 Published 1998 Journal BioDrugs Section Abstract Doc Link 18020584 Disease Relevance 0.18 Pain Relevance 0.13
We aim to test the therapeutic utility of Yttrium-90 (90Y)-radio-conjugates of a monoclonal antibody, which we showed previously to bind specifically to the abundant intracellular La ribonucleoprotein revealed in dead tumor cells after DNA-damaging treatment.


monoclonal Binding (bind) of associated with cancer
4) Confidence 0.01 Published 2009 Journal PLoS ONE Section Abstract Doc Link PMC2645682 Disease Relevance 0.40 Pain Relevance 0
In the first phase of their study, using immunohistochemistry, they found binding of monoclonal antibody B72.3 in only 6 of 45 primary non-small cell lung cancers.
monoclonal Binding (binding) of in lung associated with small cell lung cancer
5) Confidence 0.01 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.59 Pain Relevance 0
The biotin-labeled monoclonal antibody is first administered, allowing binding of the biotin-labeled monoclonal antibody to the tumor and allowing the nonspecific uptake of the biotin-labeled monoclonal antibody to be cleared.
monoclonal Spec (cleared) Binding (binding) of associated with cancer
6) Confidence 0.01 Published 2009 Journal World J Surg Oncol Section Body Doc Link PMC2653072 Disease Relevance 0.30 Pain Relevance 0.07
In vitro manipulation of the extracellular epitope of the CD20 loop alters the binding to anti-CD20 monoclonal antibodies, and thus, suggests that critical mutations in CD20 may be one mechanism of resistance (Binder et al 2006).
monoclonal Binding (binding) of
7) Confidence 0.01 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721318 Disease Relevance 0.21 Pain Relevance 0

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