INT61912

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Context Info
Confidence 0.69
First Reported 1996
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.13
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Fcgr1)
Anatomy Link Frequency
monocytes 1
Fcgr1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 28 94.32 High High
nMDA receptor antagonist 3 94.16 High High
long-term potentiation 84 91.20 High High
spinal dorsal horn 50 85.08 High High
Paracetamol 1 64.92 Quite High
c fibre 28 50.00 Quite Low
Dorsal horn neuron 1 50.00 Quite Low
chemokine 1 44.96 Quite Low
Glutamate receptor 4 10.40 Low Low
Sciatic nerve 13 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acute Chest Syndrome 35 94.44 High High
Disease 4 92.08 High High
Sickle Cell Anemia 46 84.48 Quite High
Thrombocytopenic Purpura 2 75.00 Quite High
Targeted Disruption 5 69.52 Quite High
Nose Bleeds 1 68.88 Quite High
Ecchymosis 1 68.32 Quite High
Adult Respiratory Distress Syndrome 1 65.60 Quite High
Exanthema 1 59.72 Quite High
Wheal 1 59.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data indicate that intravenous monoclonal antibody 197 induces specific down-modulation of Fc gamma RI expression on monocytes.
Gene_expression (expression) of Fc gamma RI in monocytes
1) Confidence 0.69 Published 1996 Journal Br. J. Haematol. Section Abstract Doc Link 8616043 Disease Relevance 0.39 Pain Relevance 0.06
Additionally, sickle PMNs at baseline have increased expression of the high-affinity Fc receptor CD64; this receptor is even more pronounced during crisis [28,29].
Gene_expression (expression) of CD64
2) Confidence 0.17 Published 2001 Journal Respir Res Section Body Doc Link PMC59517 Disease Relevance 0.74 Pain Relevance 0
g, Sigma, St Luis, Missouri, USA), the human IgG-Fc fragment (Fc control, 2 ?
Gene_expression (fragment) of IgG-Fc
3) Confidence 0.08 Published 2009 Journal Mol Pain Section Body Doc Link PMC2704201 Disease Relevance 0 Pain Relevance 0.35

General Comments

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