INT61915

Context Info Confidence 0.02 First Reported 1996 Last Reported 1996 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.43 Pain Relevance 0.06

plasma membrane (Fcgr1, Slc3a2) transport (Slc3a2) carbohydrate metabolic process (Slc3a2)

Fcgr1 (Mus musculus) Slc3a2 (Mus musculus)

Pain Link Frequency Relevance Heat Paracetamol 1 57.68

Disease Link Frequency Relevance Heat Thrombocytopenic Purpura 2 95.32 Increased Venous Pressure Under Development 1 70.32 Wheal 1 68.64 Exanthema 1 67.36 Ecchymosis 1 50.64 Nose Bleeds 1 49.44

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

It vitro studies have demonstrated that the monoclonal antibody 197 (subclass IgG2a) binds to two distinct epitopes of Fc gamma RI, with the constant domain binding to the Fc-binding portion of the Fc gamma RI and the variable domain binding to a different epitope, resulting in crosslinking and modulation of this receptor.

Fc gamma RI Binding (binds) of monoclonal

1) Confidence 0.02 Published 1996 Journal Br. J. Haematol. Section Abstract Doc Link 8616043 Disease Relevance 0.43 Pain Relevance 0.06

General Comments

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