INT62049

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Context Info
Confidence 0.18
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 5
Disease Relevance 6.93
Pain Relevance 2.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Lta) extracellular space (Lta) extracellular region (Lta)
Anatomy Link Frequency
mononuclear cells 5
Lta (Mus musculus)
Pain Link Frequency Relevance Heat
Multiple sclerosis 55 99.54 Very High Very High Very High
Inflammation 5 97.70 Very High Very High Very High
cytokine 10 92.28 High High
Neuritis 10 85.12 High High
Disease Link Frequency Relevance Heat
Demyelinating Disease 55 99.54 Very High Very High Very High
Neurological Disease 5 98.14 Very High Very High Very High
INFLAMMATION 5 97.70 Very High Very High Very High
Viral Meningitis 5 97.34 Very High Very High Very High
Necrosis 15 92.36 High High
Cancer 15 92.00 High High
Optic Neuritis 10 85.60 High High
Disease 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Positive correlations were observed in multiple sclerosis between TNF-alpha and LT mRNA expressing blood mononuclear cells, MBP-reactive TNF-alpha and LT mRNA expressing cells, and TNF-alpha and interferon-gamma (INF-gamma) mRNA expressing mononuclear cells.
Transcription (expressing) of LT in mononuclear cells associated with multiple sclerosis
1) Confidence 0.18 Published 1996 Journal Brain Section Abstract Doc Link 8624683 Disease Relevance 1.49 Pain Relevance 0.61
Positive correlations were observed in multiple sclerosis between TNF-alpha and LT mRNA expressing blood mononuclear cells, MBP-reactive TNF-alpha and LT mRNA expressing cells, and TNF-alpha and interferon-gamma (INF-gamma) mRNA expressing mononuclear cells.
Transcription (expressing) of LT in mononuclear cells associated with multiple sclerosis
2) Confidence 0.18 Published 1996 Journal Brain Section Abstract Doc Link 8624683 Disease Relevance 1.50 Pain Relevance 0.58
Positive correlations were observed in multiple sclerosis between TNF-alpha and LT mRNA expressing blood mononuclear cells, MBP-reactive TNF-alpha and LT mRNA expressing cells, and TNF-alpha and interferon-gamma (INF-gamma) mRNA expressing mononuclear cells.
Transcription (expressing) of LT in mononuclear cells associated with multiple sclerosis
3) Confidence 0.13 Published 1996 Journal Brain Section Abstract Doc Link 8624683 Disease Relevance 1.55 Pain Relevance 0.67
Compared with patients with aseptic meningo-encephalitis, non-inflammatory neurological diseases and healthy controls, the multiple sclerosis patients had elevated numbers of TNF-alpha and LT mRNA expressing mononuclear cells in blood when enumerated without previous culture, and also after culture with MBP.
Transcription (expressing) of LT in mononuclear cells associated with multiple sclerosis, neurological disease, inflammation and viral meningitis
4) Confidence 0.13 Published 1996 Journal Brain Section Abstract Doc Link 8624683 Disease Relevance 1.30 Pain Relevance 0.44
We describe the use of in situ hybridization with radiolabelled cDNA oligonucleotide probes to detect and enumerate TNF-alpha and LT mRNA expressing mononuclear cells without culture, and after culture in the presence of myelin basic protein (MBP), control antigens or without antigen.
Transcription (expressing) of LT in mononuclear cells
5) Confidence 0.13 Published 1996 Journal Brain Section Abstract Doc Link 8624683 Disease Relevance 1.10 Pain Relevance 0.37

General Comments

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