INT62164

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 1996
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.49
Pain Relevance 0.47

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (PTGS2) aging (Il1b) endoplasmic reticulum (PTGS2)
enzyme binding (PTGS2) protein complex (PTGS2) cytoplasm (PTGS2)
Il1b (Rattus norvegicus)
PTGS2 (Homo sapiens)
Pain Link Frequency Relevance Heat
dexamethasone 1 98.40 Very High Very High Very High
Inflammation 1 92.32 High High
Arthritis 1 91.04 High High
cINOD 3 86.40 High High
COX-2 inhibitor 1 72.40 Quite High
rheumatoid arthritis 1 63.28 Quite High
Osteoarthritis 1 51.28 Quite High
Rheumatism 1 47.12 Quite Low
Pain 2 46.16 Quite Low
COX2 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 92.32 High High
Arthritis 1 91.04 High High
Rheumatoid Arthritis 1 63.28 Quite High
Disease 2 56.00 Quite High
Osteoarthritis 1 51.28 Quite High
Rheumatic Diseases 1 47.12 Quite Low
Pain 2 46.16 Quite Low
Chronic Disease 1 43.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inducible cyclooxygenase-2 (COX-2), but not constitutive COX-1, can be upregulated in rheumatoid synovial tissue by interleukin-1 beta and phorbol esters and is inhibited by dexamethasone.
interleukin-1 beta Positive_regulation (upregulated) of cyclooxygenase-2 associated with dexamethasone
1) Confidence 0.00 Published 1996 Journal Scand. J. Rheumatol. Suppl. Section Abstract Doc Link 8628978 Disease Relevance 0.49 Pain Relevance 0.47

General Comments

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