INT62176

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Context Info
Confidence 0.00
First Reported 1996
Last Reported 2000
Negated 0
Speculated 0
Reported most in Title
Documents 2
Total Number 2
Disease Relevance 0.69
Pain Relevance 0.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (PTGS2, Ptgs1) cytoplasm (PTGS2, Ptgs1) lipid binding (PTGS2, Ptgs1)
oxidoreductase activity (PTGS2, Ptgs1) nucleus (PTGS2, Ptgs1) nuclear envelope (Ptgs1)
PTGS2 (Homo sapiens)
Ptgs1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cINOD 3 99.56 Very High Very High Very High
Inflammation 2 99.32 Very High Very High Very High
COX2 1 99.22 Very High Very High Very High
cOX1 1 99.22 Very High Very High Very High
Analgesic 2 97.84 Very High Very High Very High
COX-2 inhibitor 3 86.72 High High
rheumatoid arthritis 4 80.96 Quite High
visual analogue scale 1 64.24 Quite High
Pain 2 42.80 Quite Low
tolerance 2 27.28 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 99.32 Very High Very High Very High
Toxicity 1 83.60 Quite High
Rheumatoid Arthritis 4 80.96 Quite High
Pain 2 42.80 Quite Low
Ulcers 1 25.00 Low Low
Hemorrhage 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Meloxicam is a new non-steroidal anti-inflammatory drug (NSAID), which has a higher activity against cyclooxygenase-2 (COX-2) than against cyclooxygenase-1 (COX-1), with potentially high anti-inflammatory and analgesic action.
cyclooxygenase-2 Binding (activity) of cyclooxygenase-1 associated with inflammation, analgesic and cinod
1) Confidence 0.00 Published 1996 Journal Br. J. Rheumatol. Section Abstract Doc Link 8630633 Disease Relevance 0.43 Pain Relevance 0.45
Fluorescence quenching analysis of the association and dissociation of a diarylheterocycle to cyclooxygenase-1 and cyclooxygenase-2: dynamic basis of cyclooxygenase-2 selectivity.
cyclooxygenase-2 Binding (association) of cyclooxygenase-1 associated with cox1
2) Confidence 0.00 Published 2000 Journal Biochemistry Section Title Doc Link 10821698 Disease Relevance 0.26 Pain Relevance 0.35

General Comments

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