INT62250

Context Info Confidence 0.00 First Reported 1996 Last Reported 1996 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0.65

signal transduction (Adrb1) oxidoreductase activity (Fdft1) endoplasmic reticulum (Fdft1) plasma membrane (Adrb1) nucleus (Adrb1) transferase activity, transferring alkyl or aryl (other than methyl) groups (Fdft1)

Anatomy Link Frequency neuronal 1 Fdft1 (Rattus norvegicus) Adrb1 (Mus musculus)

Pain Link Frequency Relevance Heat Clonidine 10 100.00 Somatostatin 6 100.00 agonist 1 100.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effects of the alpha-2 adrenoceptor agonist clonidine (CLO) on the growth hormone (GH) regulatory neuronal systems, growth hormone-releasing hormone (GHRH) and somatostatin (SS), were studied in adult male rats given a single or a short-term administration (1, 3 and 6 days) of the drug.

SS Regulation (effects) of adrenoceptor in neuronal associated with somatostatin, agonist and clonidine

1) Confidence 0.00 Published 1996 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 8632352 Disease Relevance 0 Pain Relevance 0.65

General Comments

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