INT62256

Context Info Confidence 0.25 First Reported 1996 Last Reported 2009 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 3 Disease Relevance 0.53 Pain Relevance 0.10

mitochondrion (Bdh1) oxidoreductase activity (Bdh1) nucleus (Bdh1)

Anatomy Link Frequency skeletal muscle 2 Bdh1 (Mus musculus)

Pain Link Frequency Relevance Heat Pain 1 96.16 cytokine 2 5.00 anesthesia 2 5.00 Inflammatory response 2 5.00

Disease Link Frequency Relevance Heat Myocardial Infarction 5 99.88 Pain 1 96.16 Accelerated Idioventricular Rhythm 1 84.08 Targeted Disruption 14 5.00 Hypoxia 4 5.00 Adhesions 4 5.00 Shock 4 5.00 Osteogenic Sarcomas 2 5.00 Necrosis 2 5.00 Down Syndrome 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In the same analysis, genes that encode proteins in contractile apparatus (Myh3 and Myl3), signaling and transcriptional regulation (Hif3, Camkk2, Myog and Ppara), metabolism (Bdh1 and Acsl1), neuromuscular junction (Chrng) and humoral regulation (Fgf4 and Il1b) along with many other genes are now confirmed to be controlled by the p38 MAPK pathway in skeletal muscle.

Regulation (regulation) of Bdh1 in skeletal muscle

1) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0 Pain Relevance 0

In the same analysis, genes that encode proteins in contractile apparatus (Myh3 and Myl3), signaling and transcriptional regulation (Hif3, Camkk2, Myog and Ppara), metabolism (Bdh1 and Acsl1), neuromuscular junction (Chrng) and humoral regulation (Fgf4 and Il1b) along with many other genes are now confirmed to be controlled by the p38 MAPK pathway in skeletal muscle.

Regulation (regulation) of Bdh1 in skeletal muscle

2) Confidence 0.25 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2775956 Disease Relevance 0 Pain Relevance 0

Effects of UK and rtPA on continuous multilead ST-segment analysis and cardiac proteins (creatine kinase and its isoenzyme CK-MB, aspartate transaminase and hydroxybutyrate dehydrogenase) were analyzed during 24 hours following onset of therapy.

Regulation (Effects) of hydroxybutyrate dehydrogenase

3) Confidence 0.01 Published 1996 Journal Jpn Heart J Section Abstract Doc Link 8632624 Disease Relevance 0.53 Pain Relevance 0.10

General Comments

This test has worked.