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Context Info
Confidence 0.02
First Reported 1995
Last Reported 2008
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.51
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

isomerase activity (PTGES2) cytosol (PTGES2) mitochondrion (PTGES2)
Golgi apparatus (PTGES2) nucleus (PTGES2) DNA binding (PTGES2)
PTGES2 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 1 98.20 Very High Very High Very High
aspirin 1 96.84 Very High Very High Very High
Inflammatory stimuli 1 90.88 High High
metalloproteinase 1 90.16 High High
Inflammation 2 75.00 Quite High
cytokine 2 25.00 Low Low
Pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 4 98.08 Very High Very High Very High
Intervertebral Disk Degeneration 4 90.24 High High
Cancer 1 75.00 Quite High
Pain 1 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Aspirin and other currently available non-steroidal anti-inflammatory drugs that inhibit prostaglandin synthase activity do not effectively discriminate between the inducible prostaglandin synthase 2 and constitutive prostaglandin synthase 1 enzymes.
Positive_regulation (inducible) of prostaglandin synthase 2 associated with aspirin, inflammation and cinod
1) Confidence 0.02 Published 1995 Journal Bioessays Section Abstract Doc Link 8634064 Disease Relevance 0.34 Pain Relevance 0.23
RNA was isolated for reverse transcription polymerase chain reaction (RT-PCR) analysis of gene expression, conditioned media analyzed for accumulation of nitric oxide (NO) and prostaglandin E-2 (PGE-2), and proteoglycan synthesis measured after 10 days.
Spec (analyzed) Positive_regulation (accumulation) of prostaglandin E-2
2) Confidence 0.01 Published 2008 Journal J. Orthop. Res. Section Abstract Doc Link 18302237 Disease Relevance 0.17 Pain Relevance 0.05

General Comments

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