INT6232

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Context Info
Confidence 0.21
First Reported 1992
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 1.67
Pain Relevance 1.76

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
spinal 1
spinal cord 1
Col6a6 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 14 100.00 Very High Very High Very High
Eae 8 99.82 Very High Very High Very High
Sciatic nerve 3 99.34 Very High Very High Very High
Spontaneous pain 2 98.08 Very High Very High Very High
allodynia 1 96.32 Very High Very High Very High
Thermal hyperalgesia 4 95.12 Very High Very High Very High
Dorsal horn 2 87.24 High High
Pain 4 75.00 Quite High
qutenza 3 75.00 Quite High
nMDA receptor 1 75.00 Quite High
Disease Link Frequency Relevance Heat
Injury 9 99.82 Very High Very High Very High
Pain 3 98.08 Very High Very High Very High
Neuropathic Pain 6 96.92 Very High Very High Very High
Hyperalgesia 4 95.12 Very High Very High Very High
Nociception 2 90.64 High High
Diabetic Nephropathy 2 75.00 Quite High
Paralysis 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Sciatic nerve ligation produced a significant increase in spinal cord metabolic activity in four sampling regions (laminae I-IV, V-VI, VII and VIII-IX) of lumbar segments compared to sham-operated rats.
Positive_regulation (increase) of V-VI in spinal cord associated with sciatic nerve and spinal cord
1) Confidence 0.21 Published 1992 Journal Pain Section Abstract Doc Link 1325049 Disease Relevance 0.51 Pain Relevance 0.68
Interestingly, RTX treatment significantly attenuated the CCI-induced upregulation of NR1 and pNR1 in spinal laminae I-II and V-VI, but not laminae III-IV as compared with that of vehicle-treated CCI rats.
Positive_regulation (upregulation) of V-VI in spinal associated with eae
2) Confidence 0.01 Published 2008 Journal Eur J Pain Section Abstract Doc Link 17933570 Disease Relevance 1.16 Pain Relevance 1.08

General Comments

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